Human Biology (MindTap Course List)
11th Edition
ISBN: 9781305112100
Author: Cecie Starr, Beverly McMillan
Publisher: Cengage Learning
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Chapter 19, Problem 7CT
Summary Introduction
To explain: The probability that the children carry the sickle-cell trait and are sickle-cell anemic.
Introduction: Homozygous condition is when the same allele of a gene is present on both the homologous chromosomes either dominant or recessive. Heterozygous condition is where different alleles of the gene are present on both the homologous chromosomes where one is dominant and the other is recessive. Sickle-cell anemia occurs due to the homozygous recessive allele that changes the
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Sickle-cell disease is an autosomal recessive genetic disorder. How many mutated hemoglobin alleles do people with sickle-cell disease have?
Sickle cell anemia is caused by an individual carrying two recessive copies of the hemoglobin gene (hemoglobin gene is labeled Hb, and the recessive version is Hbs). Thus, to have sickle cell anemia, a person must have the genotype HbSHbS. A person that is HbAHbA carries two copies of the normal hemoglobin gene and does not have sickle cell anemia. A person that is heterozygous (HbAHbS) produces enough normal hemoglobin to not have sickle cell anemia but is also resistant to malaria. People that are heterozygous are called “carriers” because they carry the recessive allele but do not express the recessive phenotype.
a. A couple are both resistant to malaria but do not have sickle cell anemia. Draw a Punnett square to represent this cross.
b. What is the probability that the couple has three children where one child does not have a recessive allele, one child is resistant to malaria and does not have sickle cell anemia, and one child has sickle cell anemia?
Suppose two parents are healthy carriers of the sickle cell allele. The genotype of
each parent is HbAHbS (HbAis the normal allele, and HbS is the sickle-cell allele).How likely is it for a child of these parents to have sickle cell anemia (HbSHbS)?
Chapter 19 Solutions
Human Biology (MindTap Course List)
Ch. 19 - Define the difference between (a) gene and allele,...Ch. 19 - Prob. 2RQCh. 19 - What is probability, and how is it applied in...Ch. 19 - What is independent assortment? Does independent...Ch. 19 - Alleles are ___________. a. alternate forms of a...Ch. 19 - A heterozygote has _____. a. only one of the...Ch. 19 - Prob. 3SQCh. 19 - Offspring of a cross AA aa are ______. a. all AA...Ch. 19 - Prob. 5SQCh. 19 - Prob. 6SQ
Ch. 19 - Which statement best fits the principle of...Ch. 19 - Prob. 8SQCh. 19 - Prob. 9SQCh. 19 - Prob. 10SQCh. 19 - One gene has alleles A and a. Another has alleles...Ch. 19 - Still referring to Problem 1, what will be the...Ch. 19 - Go back to Problem 1, and assume you now study a...Ch. 19 - The young woman shown at right has albinismvery...Ch. 19 - When you decide to breed your Labrador retriever...Ch. 19 - The ABO blood system has been used to settle cases...Ch. 19 - Prob. 7CTCh. 19 - A man is homozygous dominant for ten different...Ch. 19 - Prob. 9CTCh. 19 - Bill and Marie each have flat feet, long...Ch. 19 - You decide to breed a pair of guinea pigs, one...
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- Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?arrow_forwardWhy do unrelated children with a disorder such as Down syndrome resemble each other more closely than they do their siblings?arrow_forwardIf diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this an indication that there is a genetic contribution to these traits? What would you do to confirm that genetics is involved in this condition?arrow_forward
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- Given that the normal hemoglobin allele (H) is dominant to the sickle-cell allele (h), each time two Hh individuals have a child together, what is the chance that the child will have sickle-cell disease? (a) 0% (b) 75% (c) 25% (d) 50% (e) 100%arrow_forwardTwo parents with blood types A and O have a child who has type O blood. What is the probability that their next child will be type A blood group?arrow_forwardJan and Michael are both carriers for the cystic fibrosis allele. If Jan and Michael have three children with the disease and then Jan becomes pregant with fratnernal twins, what is the probability that both twins will also have the disease?arrow_forward
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