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Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892

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BuyFindarrow_forward

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892
Textbook Problem

What is the principle behind whole-genome shotgun sequencing of genomes?

Summary Introduction

To review:

The principle behind the whole-genome shotgun sequencing of genomes.

Introduction:

The whole genome sequencing (WGS) refers to the procedure that involves the determination of the complete sequence of DNA (deoxyribonucleic acid) of the genome of an organism at a single time. The WGS is widely used as a research tool and is recently introduced in the clinics too.

Explanation

There are various techniques that are used to sequence the wahole genome of an organism. The whole genome shotgun sequencing is one of the techniques. This technique involves the breakdown of the entire genome into thousands of small fragments. These fragments are random and overlapping in nature. Then, the small-sized fragments are cloned and sequenced...

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