Concept explainers
The accompanying pedigree shows the transmission of a
(a) Give the genotype(s) possible for each member of the family, assuming the trait is autosomal dominant.
(b) Give the genotype(s) possible for each member of the family, assuming the trait is autosomal recessive.
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- Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?arrow_forwardGiven the following pedigree (note that C7C, M4C, N2X, H6C, G9X, J1C, B8X, and P2X are the names of animals): arrow_forwardA couple who are about to get married learn from studying their family histories that, in both their families, theirunaffected grandparents had siblings with cystic fibrosis(a rare autosomal recessive disease).a. If the couple marries and has a child, what is theprobability that the child will have cystic fibrosis?b. If they have four children, what is the chance that thechildren will have the precise Mendelian ratio of 3:1 fornormal:cystic fibrosis?c. If their first child has cystic fibrosis, what is theprobability that their next three children will be normal?arrow_forward
- The following pedigree shows what type of inheritance?arrow_forwardCould the pedigree in Figure 2-31 be explained as an autosomal dominant disorder? Explain.arrow_forwardGiven the following pedigree: Is the trait autosomal or sex-linked? Is the trait dominant or recessive? Based only on the information given, what is the probability that I-2 is heterozygous? Give the genotypes of individuals II-3, II-4. What is the probability that individual III-1 is purebreeding?arrow_forward
- From this pedigree is it dominant or recessive. Is ur autosomal or sex-linked?arrow_forwardFor this pedigree, give the most likely mode of inheritance, assuming that the trait is rare. For the pedigree, what is the probability that III-4 and III-5 will have a boy AND he will be affected?arrow_forwardIs this pedigree autosomal dominant, autosomal recessive, or X-linked recressive? Can you please label each square or circle with the correct genotypes?arrow_forward
- When examining a human pedigree, what features do you look forto distinguish between X-linked recessive inheritance and autosomal recessive inheritance? How would you distinguish X-linkeddominant inheritance from autosomal dominant inheritance in ahuman pedigree?arrow_forwardidentify each pedigree a and b as autosomal recessive or autosomal dominant. Write all the genotypes in the pedigreearrow_forwardWhat is the most likely pattern of inheritance for this disorder? (Is it autosomal dominant? Autosomal recessive? X-linked dominant? X-linked recessive? Y-linked? Mitochondrial?) Please include two specific pieces of evidence, present within the pedigree, that indicate that this pattern is most likely, as opposed to any other potential pattern. You may assume that the gene responsible for the trait is fully penetrant.arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning