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Biology: The Unity and Diversity o...

15th Edition
Cecie Starr + 3 others
Publisher: Cengage Learning
ISBN: 9781337408332

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Section
BuyFindarrow_forward

Biology: The Unity and Diversity o...

15th Edition
Cecie Starr + 3 others
Publisher: Cengage Learning
ISBN: 9781337408332
Chapter 21, Problem 2CT
Textbook Problem
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Apicomplexans evolved from a photosynthetic ancestor and have the remnant of a chloroplast. This organelle no longer acts in photosynthesis, but remains essential to the protist. Why might targeting this organelle yield an antimalarial drug with minimal side effects in humans?

Summary Introduction

To explain: The reason why targeting the chloroplast organelle yields an antimalarial drug with minimum side effects in humans.

Concept introduction: Apicomplexans are intracellular parasites that cause the diseases such as malaria, toxoplasmosis, and eimeriosis. They are single-celled eukaryotic organelles that evolved from the photosynthetic algae. A remnant chloroplast called the apicoplast is present in them, which is essential for the growth and development of the parasite and is a potential target for drug therapy.

Explanation of Solution

Apicoplasts are the organelles discovered in the apicomplexan parasites, which are a remnant of chloroplast. Like the mitochondria and chloroplast, it contains its own DNA. Apicoplast shares evolutionary similarities with chloroplast and prokaryotes like cyanobacteria. They can be used as an attractive target for known antibiotics and herbicides.

Humans do not have chloroplast in their cell...

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