ОН + Cl, + Me,NH CI MeO MeO Venlafaxine Anisole Сyclo- hexanone Chloroacetyl Dimethyl- amine chloride

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter24: Amines And Heterocycles
Section24.SE: Something Extra
Problem 48AP
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Show how the antidepressant venlafaxine (Effexor) can be synthesized from these
readily available starting materials. Is venlafaxine chiral? If so, how many of the possible stereoisomers are formed in this synthesis?

ОН
+ Cl,
+ Me,NH
CI
MeO
MeO
Venlafaxine
Anisole
Сyclo-
hexanone
Chloroacetyl Dimethyl-
amine
chloride
Transcribed Image Text:ОН + Cl, + Me,NH CI MeO MeO Venlafaxine Anisole Сyclo- hexanone Chloroacetyl Dimethyl- amine chloride
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