Concept explainers
How does the metal ion in carboxypeptidase A increase the enzyme’s catalytic activity
Interpretation:
The metal ion in carboxypetidase A increases the catalytic activity of the enzyme; this has to be explained.
Explanation of Solution
Carboxypetidase A is a digestive enzyme. It hydrolyzes the carboxyl terminal peptide bond and it prefers bulky and aliphatic residues.
Proposed mechanism for the catalytic reaction of carboxypetidase is given in figure 1.
Figure 1
The metal ion present in the carboxypeptidase A enzyme is Zinc metal.
This metal ion
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Chapter 23 Solutions
MASTERINGCHEM FOR ORGANIC CHEM STANDAL