Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 25.2, Problem 1COMQ
Summary Introduction
Introduction:
A mutation is defined as an abnormality in the gene expression that can cause alteration in the number and thestructure of chromosomes. A full chromosomal set of an individual is known as karyotype. Abnormality in the number of chromosomes in an individual is referred to as aneuploidy. It can be of different types, such as, trisomy, monosomy, tetrasomy, and many more.
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What is a haplotype?a. A species with one set of chromosomesb. A cell with one set of chromosomesc. The linkage of alleles or molecular markers on a chromosomed. All of the above describe a haplotype.
When preparing a karyotype, which of the following steps isconducted?a. Treat the cells with a drug that causes them to begin celldivision.b. Treat the cells with a hypotonic solution that causes them toswell.c. Expose the cells to chemical dyes that bind to the chromosomes and stain them.d. All of the above
A geneticist determines that the order of four genes on a specific chromosome is CABD because the recombination frequencies were 35% for C-D, 24% for A-D, 23% for B-D, and 10% for A-B. What has the geneticist constructed?
A. a physical map
B. a karyotype
C. a cytogenic map
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Chapter 25 Solutions
Genetics: Analysis and Principles
Ch. 25.1 - Which of the following wouldnotbe consistent with...Ch. 25.1 - 2. Assuming complete penetrance, which type of...Ch. 25.1 - 3. Which of the following is not a common...Ch. 25.1 - Prob. 4COMQCh. 25.2 - Prob. 1COMQCh. 25.2 - Haplotype association studies are aimed at the...Ch. 25.3 - 1. Which of the following is not a method used in...Ch. 25.3 - 2. Which of the following prenatal genetic testing...Ch. 25.4 - Prob. 1COMQCh. 25.5 - 1. An oncogene is produced from a ________that has...
Ch. 25.5 - Which of the following is a type of genetic change...Ch. 25.5 - 3. Tumor-suppressor genes promote cancer...Ch. 25.5 - 4. Normal (nonmutant) tumor-suppressor genes often...Ch. 25.5 - Prob. 5COMQCh. 25.6 - Prob. 1COMQCh. 25 - 1. With regard to pedigree analysis, make a list...Ch. 25 - 2. Explain, at the molecular level, why human...Ch. 25 - 3. Many genetic disorders exhibit locus...Ch. 25 - Prob. 4CONQCh. 25 - Prob. 5CONQCh. 25 - Figure 25.1 illustrates albinism in two different...Ch. 25 - Prob. 7CONQCh. 25 - Prob. 8CONQCh. 25 - Ehler-Danlos syndrome is a rare disorder caused by...Ch. 25 - 10. Hurler syndrome is due to a mutation in a gene...Ch. 25 - Like Hurler syndrome, Fabry disease involves an...Ch. 25 - Achondroplasia is a rare form of dwarfism caused...Ch. 25 - Prob. 13CONQCh. 25 - 14. Marfan syndrome is due to a mutation in a...Ch. 25 - 15. Sandhoff disease is due to a mutation in a...Ch. 25 - Describe the two assumptions that underlie the...Ch. 25 - Prob. 17CONQCh. 25 - What is a prion? Explain how a prion relies on...Ch. 25 - 19. Some people have a genetic predisposition for...Ch. 25 - What is the difference between an oncogene and a...Ch. 25 - Prob. 21CONQCh. 25 - Prob. 22CONQCh. 25 - Prob. 23CONQCh. 25 - Prob. 24CONQCh. 25 - Prob. 25CONQCh. 25 - Prob. 26CONQCh. 25 - Prob. 27CONQCh. 25 - With regard to cancer cells, which of the...Ch. 25 - Prob. 29CONQCh. 25 - 1. Which of the following experimental...Ch. 25 - Prob. 2EQCh. 25 - 3. What is meant by the term genetic testing? How...Ch. 25 - Prob. 4EQCh. 25 - 5. Chapter 21 describes a method known as Western...Ch. 25 - 6. An experimental assay for the blood-clotting...Ch. 25 - 7. Discuss ways to distinguish whether a...Ch. 25 - 8. The codon change (Gly-12 to Val-12) in...Ch. 25 - Explain how DNA microarrays are used in molecular...Ch. 25 - Make a list of the benefits that may arise from...Ch. 25 - 2. Our government has finite funds to devote to...Ch. 25 - Prob. 3QSDC
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- What is a haplotype?a. A species with one set of chromosomesb. A cell with one set of chromosomesc. The linkage of alleles or molecular markers along achromosomed. All of the abovearrow_forwardWhen preparing a karyotype, which of the following steps is conducted?a. Treat the cells with a chemical that causes them to begin cell division.b. Treat the cells with a hypotonic solution that causes them to swell.c. Expose the cells to chemical dyes that bind to the chromosomesand stain them.d. All of the above steps are carried out.arrow_forwardFor each species, all ______ in the complete set of chromosomes is/are the _______. a. genomes; phenotype c. mRNA; start of cDNA b. DNA; genome d. cDNA; start of mRNAarrow_forward
- Which recombination frequency corresponds to independent assortment and the absence of linkage? a. 0 b. 0.25 c. 0.50 d. 0.75arrow_forwardThe graph below shows the connection between 5 cities and their respective distances in kilometers:a) Propose a way to encode chromosomes.b) Define a fitness function to evaluate the quality of chromosomes.c) Generate two chromosomes and evaluate their fitness.arrow_forwardVariation in the traits of organisms may be attributable toa. gene mutations.b. alterations in chromosome structure.c. variation in chromosome number.d. all of the abovearrow_forward
- Imagine you wanted to preserve the dwindling populations of giant pandas by developing breeding programs for captive pandas around the world. To preserve the maximum genetic diversity, you want to mate the individuals that are least related to each other. Which of the following methods of analysis would be most helpful in determining which of the captive pandas were related? a. PCR b. STR analysis c. DNA microinjection d. DNA sequencingarrow_forwardWhich recombination frequency corresponds to perfect linkage and violates the law of independent assortment? a. 0 b. 0.25 c. 0.50 d. 0.75arrow_forwardFigure 4 shows the hybridization process between plant P and Q. a) Determine the sterile hybrid plant and the fertile hybrid plant. b) What is process A? c) State the chromosome number for the fertile hybrid plant.arrow_forward
- What is shown here? A. Heterotype B. Phenotype C. Karyotype D. Genotypearrow_forwardConstructing a pedigree is particularly useful when studying inheritance patterns in organisms that________ . a. produce many offspring per generation b. produce few offspring per generation c. have a very large chromosome number d. have a fast life cyclearrow_forwardUsing gene mapping techniques, explain how you could determine if two genes are located close together on a chromosome.arrow_forward
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