Concept explainers
a)
Interpretation:
The Fischer projection formula is to be converted in to a tetrahedral representation and its configuration as R or S is to be assigned.
Concept introduction:
In Fischer projection formula, a tetrahedral carbon is represented by two crossed lines. The horizontal line represents bonds coming out of the page and vertical lines represent bonds moving in to the page.
For assigning R or S configuration, the four groups attached to the chiral center are arranged in the order of priority by applying sequence rules. The molecule is then oriented in such a way that the group of lowest priority points away from the viewer. If the arrangement of highest priority to second highest priority to third highest priority is clockwise then R configuration is assigned. If the arrangement of highest priority to second highest priority to third highest priority is counterclockwise then S configuration is assigned.
To covert:
The Fischer projection formula in to a tetrahedral representation and to assign its configuration as R or S.
b)
Interpretation:
The Fischer projection formula is to be converted in to a tetrahedral representation and its configuration as R or S is to be assigned.
Concept introduction:
In Fischer projection formula, a tetrahedral carbon is represented by two crossed lines. The horizontal line represents bonds coming out of the page and vertical lines represent bonds moving in to the page.
For assigning R or S configuration, the four groups attached to the chiral center are arranged in the order of priority by applying sequence rules. The molecule is then oriented in such a way that the group of lowest priority points away from the viewer. If the arrangement of highest priority to second highest priority to third highest priority is clockwise then R configuration is assigned. If the arrangement of highest priority to second highest priority to third highest priority is counterclockwise then S configuration is assigned.
To covert:
The Fischer projection formula in to a tetrahedral representation and to assign its configuration as R or S.
c)
Interpretation:
The Fischer projection formula is to be converted in to a tetrahedral representation and its configuration as R or S is to be assigned.
Concept introduction:
In Fischer projection formula, a tetrahedral carbon is represented by two crossed lines. The horizontal line represents bonds coming out of the page and vertical lines represent bonds moving in to the page.
For assigning R or S configuration, the four groups attached to the chiral center are arranged in the order of priority by applying sequence rules. The molecule is then oriented in such a way that the group of lowest priority points away from the viewer. If the arrangement of highest priority to second highest priority to third highest priority is clockwise then R configuration is assigned. If the arrangement of highest priority to second highest priority to third highest priority is counterclockwise then S configuration is assigned.
To covert:
The Fischer projection formula in to a tetrahedral representation and to assign its configuration as R or S.
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Chapter 25 Solutions
Organic Chemistry
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- Find a constitutional isomer of C7H16 that has only one tetrahedral stereocenter and then make a Fischer projection of the R-stereoisomer, placing the group with priority 4 on top and priority 2 on bottom.arrow_forwardAssign R/S to each of the chirality centers shown below.arrow_forwardConsider a mixture that is 60% (+) enantiomer and 40% (-) enantiomer. In which direction will the mixture rotate plane-polarized light? What is the enantiomeric excess of the mixture?arrow_forward
- Draw the structure for a compound with molecular formula C2H2I2F2 a. that is optically inactive because it does not have an asymmetric center. b. that is optically inactive because it is a meso compound. c. that is optically active.arrow_forwardDraw all of the possible stereoisomers of the compound shown. Group them as enantiomeric pairs, or indicate any meso compounds. Label all stereocenters with the absolute stereochemistry (R or S).arrow_forwardSalinosporamide A, isolated from a microbe called Salinispora tropica has shown promise as an inhibitor of cancer cell growth. Select the chiral centers in the following structure; the selected centers will appear highlighted green.arrow_forward
