Concept explainers
Draw the product formed from the ring-closing metathesis of each compound. Then, devise a synthesis of each metathesis starting material from benzene, alcohols with less than five carbons, and any needed organic and inorganic reagents.
a. b.
(a)
Interpretation: The product formed from the ring-closing metathesis of given compound is to be drawn, and the synthesis of metathesis starting material using
Concept introduction: The ring-closing metathesis (RCM) by Grubbs catalyst occurs, when the starting material is diene. This reaction is facilitated under high-dilution condition as it favors intramolecular metathesis instead of intermolecular metathesis.
Answer to Problem 26.49P
The product formed from the ring-closing metathesis of given compound is
The synthesis of metathesis starting material using
Explanation of Solution
The given compound is a diene.
The ring-closing metathesis (RCM) by Grubbs catalyst occurs, when the starting material is diene. This reaction is facilitated under high-dilution condition as it favors intramolecular metathesis instead of intermolecular metathesis.
The product formed from the ring-closing metathesis of given compound is drawn in Figure 1.
Figure 1
The synthesis of metathesis starting material involves ten steps. The first step is Friedel-Crafts alkylation of benzene with
Figure 2
The product formed from the ring-closing metathesis of given compound is drawn in Figure 1. The synthesis of metathesis starting material using
(b)
Interpretation: The product formed from the ring-closing metathesis of given compound is to be drawn, and the synthesis of metathesis starting material using
Concept introduction: The ring-closing metathesis (RCM) by Grubbs catalyst occurs, when the starting material is diene. This reaction is facilitated under high-dilution condition as it favors intramolecular metathesis instead of intermolecular metathesis.
Answer to Problem 26.49P
The product formed from the ring-closing metathesis of given compound is,
The synthesis of metathesis starting material using
Explanation of Solution
The given compound is a diene.
The ring-closing metathesis (RCM) by Grubbs catalyst occurs, when the starting material is diene. This reaction is facilitated under high-dilution condition as it favors intramolecular metathesis instead of intermolecular metathesis.
The product formed from the ring-closing metathesis of given compound is drawn in Figure 3.
Figure 3
The synthesis of metathesis starting material involves nine steps. The first step is Friedel-Crafts alkylation of benzene with chloromethane in the presence of
Figure 4
The product formed from the ring-closing metathesis of given compound is drawn in Figure 3. The synthesis of metathesis starting material using
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Chapter 26 Solutions
Organic Chemistry