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Nucleotide Catabolism as a Source of Metabolic Energy (Integrates with Chapters I8-20 and 22.) By what pathway(s) does the ribose released upon nucleotide degradation enter intermediary metabolism and become converted to cellular energy? How many ATP equivalents can be recovered from one equivalent of ribose?

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Biochemistry

6th Edition
Reginald H. Garrett + 1 other
Publisher: Cengage Learning
ISBN: 9781305577206

Solutions

Chapter
Section
BuyFindarrow_forward

Biochemistry

6th Edition
Reginald H. Garrett + 1 other
Publisher: Cengage Learning
ISBN: 9781305577206
Chapter 26, Problem 7P
Textbook Problem
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Nucleotide Catabolism as a Source of Metabolic Energy (Integrates with Chapters I8-20 and 22.) By what pathway(s) does the ribose released upon nucleotide degradation enter intermediary metabolism and become converted to cellular energy? How many ATP equivalents can be recovered from one equivalent of ribose?

Interpretation Introduction

Interpretation:

Explanation about the requirement of ATP equivalents to be recovered from one equivalent of ribose.

Concept introduction:

Because every molecule of carbohydrate has five carbons, and every those phosphate has three carbons. Three molecules of saccharine (15 C total), during this method, five nucleotide area unit consumed, one for every simple sugar phosphate shaped. The five freshly shaped monosaccharide phosphates are then metabolized into five pyruvates, producing five NADH and ten nucleotides within the method. The five NADH created may be regenerate to fifteen nucleotide within the lepton transport chain. This produces a complete of twenty five nucleotides at this step.

Explanation of Solution

The ribose product of nucleotide degradation may be any metabolized by the monosaccharide phosphate pathway, glycolysis, and acid cycles. The method by that this happens starts with phosphorylation to ribose-5-phosphate at the expense of associate degree ATP phosphate bond and is then converted to ribulose-5-phosphate that is regenerate to monosaccharide phosphates. Every saccharine molecule can produce 1.66 simple sugar phosphate equivalents.

Because every molecule of carbohydrate has five carbons, and every those phosphate has three carbons. Three molecules of saccharine (15 C total), during this method, five nucleotide area unit consumed, one for every simple sugar phosphate shaped.

The five freshly shaped monosaccharide phosphates are then metabolized into five pyruvates, producing five NADH and ten nucleotides within the method. The five NADH created may be regenerate to fifteen nucleotide within the lepton transport chain. This produces a complete of twenty five nucleotides at this step.

The five pyruvate molecules will enter the acid cycle and are able to manufacture fifteen nucleotides per pyruvate, which supplies a complete of seventy five nucleotides from the acid cycle...

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