Brock Biology of Microorganisms, Books a la Carte Edition
Brock Biology of Microorganisms, Books a la Carte Edition
15th Edition
ISBN: 9780134626109
Author: MADIGAN, Michael T.
Publisher: Pearson Education Canada
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Chapter 27, Problem 1AQ

Antibodies of the IgA class are probably more prevalent than those of the IgG class. Explain this and define the benefits this may have for the host.

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Summary Introduction

To explain:

The importance IgA and IgG antibodies with their potential advantages and disadvantages.

Concept introduction:

Antibodies are known as immunoglobulins (Ig) are the potential receptors that can recognize unique aspects of antigen present on the pathogen. Antibodies are produced by the differentiation of B cells into plasma cells. Based on the physical, chemical, and immunological properties, antibodies are classified into five classes namely IgG, IgA, IgM, IgE, and IgA.

Explanation of Solution

IgG is the most prevalent antibody found in the human blood serum. IgG is made up of “four polypeptide chains” joined with the help of disulfide bond. IgG exhibits dimerism because it has two similar sites for antigen binding. IgG provides resistance towards the microbes which direly cause infection in the bloodstream. IgG exclusively cross the placenta to provide immunity to the developing fetus.

IgA is the major immunoglobulin present in external secretions in the form of colostrum, tears, and saliva. IgA is present in higher concentration in colostrum which provides resistance towards intestinal diseases in the newborn baby. In contrast to IgG, IgA is considered more beneficial because it acts as the first line of defense against the invasion of microbes in mucosal epithelium.

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Chapter 27 Solutions

Brock Biology of Microorganisms, Books a la Carte Edition

Ch. 27.3 - Prob. 3MQCh. 27.3 - QDescribe the structural and functional...Ch. 27.4 - Draw a complete Ig molecule and identify...Ch. 27.4 - Describe antigen binding to the CDR1, 2, and 3...Ch. 27.4 - Describe the recombination events that produce a...Ch. 27.4 - QWhich Ig chains are used to construct a complete...Ch. 27.5 - Identify the cells that display MHC class I and...Ch. 27.5 - Compare the MHC I and MHC II protein structures...Ch. 27.5 - Define the sequence of events for processing and...Ch. 27.5 - QDescribe the basic structure of class I and class...Ch. 27.6 - Define polymorphism and polygeny as they apply to...Ch. 27.6 - How does a single MHC protein present many...Ch. 27.6 - QPolymorphism implies that each different MHC...Ch. 27.7 - Prob. 1MQCh. 27.7 - Identify diversity-generating mechanisms unique to...Ch. 27.7 - Describe and compare the structural features of Ig...Ch. 27.7 - QWhat diversity-generating mechanisms function to...Ch. 27.8 - Describe the mechanism used by Tc cells to...Ch. 27.8 - Describe the effector system (the cell-killing...Ch. 27.8 - Compare and contrast the roles and activities of...Ch. 27.8 - QWhat mechanism do Tc cells use to identify and...Ch. 27.9 - Discriminate between immediate hypersensitivity...Ch. 27.9 - Provide examples and mechanisms for an...Ch. 27.9 - QHow do immediate and delayed-type...Ch. 27.10 - Describe the binding site for superantigens on T...Ch. 27.10 - Compare and contrast the immunodeficiency observed...Ch. 27.10 - Prob. 3MQCh. 27.10 - Prob. 1CRCh. 27 - Antibodies of the IgA class are probably more...Ch. 27 - Prob. 2AQCh. 27 - Polymorphism implies that each different MHC...Ch. 27 - What problems would arise if a person had a...
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