The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence. Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Question

Want to see more full solutions like this?

Answer 1

Question

Chapter 27, Problem 1E

Summary Introduction

To explain: The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence.

Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Expert Solution & Answer

Explanation of Solution

Explanation:

A 4-nt insertion is the addition of four nucleotides to the sequence. This means that the addition of one codon and one nucleotide. This addition of a codon shifts the reading frame of the gene by one nucleotide. The proper reading frame is restored by deleting a nucleotide. The reading frame usually constitutes three nucleotides called codons. The deletion of a nucleotide restores the proper reading frame and the 4-nt insertion has one codon and one additional nucleotide. Thus, the single nucleotide deletion restores the function of a protein-coding gene. The gene function cannot be restored if it is as given below:

The 4-nt insertion interrupts the codon of a function that determines the amino acid.
The 4-nt insertion creates codon amino acid that breaks the structure.
The 4-nt insertion introduced the stop codon earlier in the gene.
The 1-nt deletion occurs far from the 4-nt insertion.

A long sequence of frame-shifted codons is separated by the insertion and the deletion points, even though the reading frame was restored. Thus, the single nucleotide deletion restores the function of a protein-coding gene interrupted by the insertion of a 4-nt sequence.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 2

Question

Chapter 27, Problem 1E

Summary Introduction

To explain: The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence.

Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Expert Solution & Answer

Explanation of Solution

Explanation:

A 4-nt insertion is the addition of four nucleotides to the sequence. This means that the addition of one codon and one nucleotide. This addition of a codon shifts the reading frame of the gene by one nucleotide. The proper reading frame is restored by deleting a nucleotide. The reading frame usually constitutes three nucleotides called codons. The deletion of a nucleotide restores the proper reading frame and the 4-nt insertion has one codon and one additional nucleotide. Thus, the single nucleotide deletion restores the function of a protein-coding gene. The gene function cannot be restored if it is as given below:

The 4-nt insertion interrupts the codon of a function that determines the amino acid.
The 4-nt insertion creates codon amino acid that breaks the structure.
The 4-nt insertion introduced the stop codon earlier in the gene.
The 1-nt deletion occurs far from the 4-nt insertion.

A long sequence of frame-shifted codons is separated by the insertion and the deletion points, even though the reading frame was restored. Thus, the single nucleotide deletion restores the function of a protein-coding gene interrupted by the insertion of a 4-nt sequence.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 27, Problem 1E

Summary Introduction

To explain: The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence.

Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Expert Solution & Answer

Explanation of Solution

Explanation:

A 4-nt insertion is the addition of four nucleotides to the sequence. This means that the addition of one codon and one nucleotide. This addition of a codon shifts the reading frame of the gene by one nucleotide. The proper reading frame is restored by deleting a nucleotide. The reading frame usually constitutes three nucleotides called codons. The deletion of a nucleotide restores the proper reading frame and the 4-nt insertion has one codon and one additional nucleotide. Thus, the single nucleotide deletion restores the function of a protein-coding gene. The gene function cannot be restored if it is as given below:

The 4-nt insertion interrupts the codon of a function that determines the amino acid.
The 4-nt insertion creates codon amino acid that breaks the structure.
The 4-nt insertion introduced the stop codon earlier in the gene.
The 1-nt deletion occurs far from the 4-nt insertion.

A long sequence of frame-shifted codons is separated by the insertion and the deletion points, even though the reading frame was restored. Thus, the single nucleotide deletion restores the function of a protein-coding gene interrupted by the insertion of a 4-nt sequence.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 27, Problem 1E

Summary Introduction

To explain: The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence.

Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Expert Solution & Answer

Explanation of Solution

Explanation:

A 4-nt insertion is the addition of four nucleotides to the sequence. This means that the addition of one codon and one nucleotide. This addition of a codon shifts the reading frame of the gene by one nucleotide. The proper reading frame is restored by deleting a nucleotide. The reading frame usually constitutes three nucleotides called codons. The deletion of a nucleotide restores the proper reading frame and the 4-nt insertion has one codon and one additional nucleotide. Thus, the single nucleotide deletion restores the function of a protein-coding gene. The gene function cannot be restored if it is as given below:

The 4-nt insertion interrupts the codon of a function that determines the amino acid.
The 4-nt insertion creates codon amino acid that breaks the structure.
The 4-nt insertion introduced the stop codon earlier in the gene.
The 1-nt deletion occurs far from the 4-nt insertion.

A long sequence of frame-shifted codons is separated by the insertion and the deletion points, even though the reading frame was restored. Thus, the single nucleotide deletion restores the function of a protein-coding gene interrupted by the insertion of a 4-nt sequence.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 27, Problem 1E

Summary Introduction

To explain: The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence.

Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Expert Solution & Answer

Explanation of Solution

Explanation:

A 4-nt insertion is the addition of four nucleotides to the sequence. This means that the addition of one codon and one nucleotide. This addition of a codon shifts the reading frame of the gene by one nucleotide. The proper reading frame is restored by deleting a nucleotide. The reading frame usually constitutes three nucleotides called codons. The deletion of a nucleotide restores the proper reading frame and the 4-nt insertion has one codon and one additional nucleotide. Thus, the single nucleotide deletion restores the function of a protein-coding gene. The gene function cannot be restored if it is as given below:

The 4-nt insertion interrupts the codon of a function that determines the amino acid.
The 4-nt insertion creates codon amino acid that breaks the structure.
The 4-nt insertion introduced the stop codon earlier in the gene.
The 1-nt deletion occurs far from the 4-nt insertion.

A long sequence of frame-shifted codons is separated by the insertion and the deletion points, even though the reading frame was restored. Thus, the single nucleotide deletion restores the function of a protein-coding gene interrupted by the insertion of a 4-nt sequence.

Answer 6

Chapter 27, Problem 1E

Summary Introduction

To explain: The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence.

Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Expert Solution & Answer

Explanation of Solution

Explanation:

A 4-nt insertion is the addition of four nucleotides to the sequence. This means that the addition of one codon and one nucleotide. This addition of a codon shifts the reading frame of the gene by one nucleotide. The proper reading frame is restored by deleting a nucleotide. The reading frame usually constitutes three nucleotides called codons. The deletion of a nucleotide restores the proper reading frame and the 4-nt insertion has one codon and one additional nucleotide. Thus, the single nucleotide deletion restores the function of a protein-coding gene. The gene function cannot be restored if it is as given below:

The 4-nt insertion interrupts the codon of a function that determines the amino acid.
The 4-nt insertion creates codon amino acid that breaks the structure.
The 4-nt insertion introduced the stop codon earlier in the gene.
The 1-nt deletion occurs far from the 4-nt insertion.

A long sequence of frame-shifted codons is separated by the insertion and the deletion points, even though the reading frame was restored. Thus, the single nucleotide deletion restores the function of a protein-coding gene interrupted by the insertion of a 4-nt sequence.

Answer 7

Chapter 27, Problem 1E

Summary Introduction

To explain: The reason behind a single nucleotide deletion restoring the function of a protein-coding gene being interrupted by the insertion of a 4-nt sequence.

Concept introduction: Mutation causes some permanent changes in the nucleotide sequence. When the mutation occurs, a single nucleotide in the nucleotide sequence is deleted. This is called point mutation. This leads to irreversible changes and alters the reading frame of the gene.

Answer 8

Expert Solution & Answer

Explanation of Solution

Explanation:

A 4-nt insertion is the addition of four nucleotides to the sequence. This means that the addition of one codon and one nucleotide. This addition of a codon shifts the reading frame of the gene by one nucleotide. The proper reading frame is restored by deleting a nucleotide. The reading frame usually constitutes three nucleotides called codons. The deletion of a nucleotide restores the proper reading frame and the 4-nt insertion has one codon and one additional nucleotide. Thus, the single nucleotide deletion restores the function of a protein-coding gene. The gene function cannot be restored if it is as given below:

The 4-nt insertion interrupts the codon of a function that determines the amino acid.
The 4-nt insertion creates codon amino acid that breaks the structure.
The 4-nt insertion introduced the stop codon earlier in the gene.
The 1-nt deletion occurs far from the 4-nt insertion.

A long sequence of frame-shifted codons is separated by the insertion and the deletion points, even though the reading frame was restored. Thus, the single nucleotide deletion restores the function of a protein-coding gene interrupted by the insertion of a 4-nt sequence.