What is the Metabolic Value of NADPH in ATP Equivalents? (Integrates with Chapter 20.) The standard reduction potentials for the (NAD + /NADH) and (NADP + /NADPH) couples are identical, namely, -320 mV. Assuming the in vivo concentration ratios NAD + / NADH = 20 and NADP + /NADPH = 0.1, what is Δ G for the following reaction? NADPH + NAD + ⇌ NADP + + NADH Assuming standard state condition for the reaction, ADP + P i → ATP + H 2 O , calculate how many ATP equivalents can be for4med from ADP + P i by the energy released in this reaction.

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Biochemistry

6th Edition
Reginald H. Garrett + 1 other
Publisher: Cengage Learning
ISBN: 9781305577206
BuyFind

Biochemistry

6th Edition
Reginald H. Garrett + 1 other
Publisher: Cengage Learning
ISBN: 9781305577206

Solutions

Chapter
Section
Chapter 27, Problem 4P
Textbook Problem

What is the Metabolic Value of NADPH in ATP Equivalents? (Integrates with Chapter 20.) The standard reduction potentials for the (NAD+/NADH) and (NADP+/NADPH) couples are identical, namely, -320 mV. Assuming the in vivo concentration ratios NAD+/ NADH = 20 and NADP+/NADPH = 0.1, what is Δ G for the following reaction?

NADPH + NAD +    NADP + + NADH Assuming standard state condition for the reaction, ADP + P i ATP + H 2 O , calculate how many ATP equivalents can be for4med from ADP + Pi by the energy released in this reaction.

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