Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 27, Problem 5P
Interpretation Introduction

Interpretation:

The value of concentration of ADP and AMP if the adenylate kinase reaction is at equilibrium.

Concept introduction:

Adenylate enzyme (also called ADK or myokinase) could be a phosphotransferase catalyst that catalyzes the interconversion of purine nucleotides (ATP, ADP, and AMP). By perpetually observation phosphate ester levels within the cell, ADK plays a vital role in cellular energy physiological state.

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Phosphatidylethanolamine and PIP2 containing identical fatty acyl residues can be hydrolyzed with the same efficiency by a certain phospholipase C. Will the hydrolysis products of the two lipids have the same effect on protein kinase C? Explain.
If intracellular [ATP] = 5 mM, [ADP] = 0.5 mM, and [Pi] = 1.0 mM, calculate the concentration of AMP at pH 7 and 25°C under the condition that the adenylate kinase reaction is at equilibrium.
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