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Variations on a Theme by Mendel In homozygotes, the recessive allele h prevents the A and B antigens from being placed on the surface of cells in individuals carrying either the I A or I B allele (or both alleles). The normal H allele allows these antigens to be placed on cell surfaces. a. Predict all possible blood-type phenotypes and their ratios in a cross between HhAB × HhAB individuals. b. Among those individuals with type O blood, what genotypes are present, and in what ratios?

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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 3, Problem 36QP
Textbook Problem
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Variations on a Theme by Mendel

In homozygotes, the recessive allele h prevents the A and B antigens from being placed on the surface of cells in individuals carrying either the IA or IB allele (or both alleles). The normal H allele allows these antigens to be placed on cell surfaces.

  1. a. Predict all possible blood-type phenotypes and their ratios in a cross between HhAB × HhAB individuals.
  2. b. Among those individuals with type O blood, what genotypes are present, and in what ratios?

a.

Summary Introduction

To determine: The possible phenotypes and their ratios for the cross between the parents HhAB × HhAB.

Introduction: The human blood group is an example of codominance where the alleles for the two antigens A and B are equally dominant. It means that when the two antigens A and B are present, the blood group is AB whereas in the absence of both the antigens, the blood group is O.

Explanation of Solution

The resulting progeny from the cross between HhAB × HhAB will be as follows:

GametesHAHBhAhB
HAHHAAHHABHhAAHhAB
HBHHABHHBBHhABHhBB
hAHhAAHhAB

b.

Summary Introduction

To determine: The genotype of the individuals with blood group O.

Introduction: The individuals with the blood group O lack the surface antigens for both the blood groups A and B. Therefore, the expression of type O blood group occurs when the individual inherits both the recessive alleles. It makes  people with type O blood group to become universal donors.

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Chapter 3 Solutions

Human Heredity: Principles and Issues (MindTap Course List)
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