Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 3, Problem 9QP
Crossing Pea Plants: Mendel’s Study of Single Traits
Sickle cell anemia (SCA) is a human genetic disorder caused by a recessive allele. A couple plan to marry and want to know the probability that they will have an affected child. With your knowledge of
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Mendel crossed two Pea plants for plant height and flower color Tall plant (T) is dominant to Short Plant (t). Purple Flower (P) is dominant to white flower (p). Using the following information perform the dihybrid cross using punnett squares that will predict all possible genotypes of the offspring and list the number and description of the phenotypes of the offspring. A. One plant homozygous dominant for plant height and flower color crossed with another plant homozygous recessive for plant height and heterozygous for flower color.
Mendelian Genetics and Non-Mendelian Genetics: Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jillian is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Jacobwhose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia.
1. Give the genotypes of Jillian and Jacob.
Assuming that they will have 4 children, what is the probability that:
2. all their children will be normal?
3. they will have a son with Huntington’s disease?
4. they will have a daughter inflicted with both conditions
Neo-Mendelian Genetics: Complete dominance and overdominance
Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Mary is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibits sickle cell anemia.
What are the genotypes of Mary and Paul?
If they plan to have four children, what is the probability that:
all their children will be normal? ____________
they will have a son with Huntington’s disease? ___________
they will have a daughter inflicted with both conditions?____________
Chapter 3 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 3.4 - Why do scientists design experiments to disprove...Ch. 3.4 - Should Ockhams razor be considered an irrefutable...Ch. 3.7 - Prob. 1EGCh. 3.7 - For most cases, a p value of 0.05 is used to...Ch. 3 - Prob. 1CSCh. 3 - Prob. 2CSCh. 3 - Prob. 3CSCh. 3 - Prob. 1QPCh. 3 - Crossing Pea Plants: Mendels Study of Single...Ch. 3 - Crossing Pea Plants: Mendels Study of Single...
Ch. 3 - Prob. 4QPCh. 3 - Crossing Pea Plants: Mendels Study of Single...Ch. 3 - Prob. 6QPCh. 3 - Crossing Pea Plants: Mendels Study of Single...Ch. 3 - Crossing Pea Plants: Mendels Study of Single...Ch. 3 - Crossing Pea Plants: Mendels Study of Single...Ch. 3 - Crossing Pea Plants: Mendels Study of Single...Ch. 3 - Crossing Pea Plants: Mendels Study of Single...Ch. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - Prob. 14QPCh. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - Prob. 17QPCh. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - More Crosses with Pea Plants: The Principle of...Ch. 3 - Meiosis Explains Mendels Results: Genes Are on...Ch. 3 - Meiosis Explains Mendels Results: Genes Are on...Ch. 3 - Meiosis Explains Mendels Results: Genes Are on...Ch. 3 - Prob. 26QPCh. 3 - Prob. 27QPCh. 3 - Variations on a Theme by Mendel A characteristic...Ch. 3 - Prob. 29QPCh. 3 - Variations on a Theme by Mendel Pea plants usually...Ch. 3 - Prob. 31QPCh. 3 - Prob. 32QPCh. 3 - Prob. 33QPCh. 3 - Prob. 34QPCh. 3 - Prob. 35QPCh. 3 - Prob. 36QP
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- Mendel performs a cross using a true-breeding pea plant with round, yellow seeds and a true- breeding pea plant with green, wrinkled seeds. What is the probability that offspring will have green, round seeds? Calculate the probability for the F1 and F2 generations.arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?arrow_forward
- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?arrow_forwardSickle cell anemia is a human genetic disorder caused by an autosomal recessive allele. A couple plan to marry and want to know the probability that they will have an affected child. With your knowledge of Mendelian inheritance, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA or (2) the man is affected by the disorder but the woman has no family history of SCA?arrow_forwardThe diagrams represent two human somatic cells, one from a female and one from a male, and the letters in the cells represent alleles for two different traits. Male Female B = Brown hair (dominant) b = Blond hair (recessive) E = Brown eyes (dominant) e = Blue eyes (recessive) According to Mendel’s Law of Independent Assortment, what are the allele combinations expected in each of the sperm cells and what combinations are expected in each of the eggs produced by these cells during meiosis? One sperm fertilized one egg, and the resulting child has blond hair and brown eyes. How is this possible given the parents' genotypes?arrow_forward
- (Recessive Sex-linked Trait) A family has four children, two girls and two boys. One girl and one boy are color-blind. Are their parents color-blind? Draw and Label a pedigree.arrow_forward. When Mendel crossed a large number of tall pea plants with short pea plants, all F1 plants were tall. The F2 generation was created by self-pollinating the F1 plants. Complete a genetic cross of F2 to show the genotypes and phenotypes of the offspring. State the ratio of phenotypes expected in the F2 offspring. Mendel’s First Law of inheritance states that, “…the alleles of a given locus segregate into separate gametes.” Explain how the genetic diagram above proves this law. (AC 2.1) can i get help please.arrow_forwardPlease explain why sex linked recessive traits are inherited by the son from his mother. If a mother is a carrier, what percentage of her sons will have the trait? Please give me example of sex linked recessive trait.arrow_forward
- A couple who are about to get married learn from studying their family histories that, in both their families, theirunaffected grandparents had siblings with cystic fibrosis(a rare autosomal recessive disease).a. If the couple marries and has a child, what is theprobability that the child will have cystic fibrosis?b. If they have four children, what is the chance that thechildren will have the precise Mendelian ratio of 3:1 fornormal:cystic fibrosis?c. If their first child has cystic fibrosis, what is theprobability that their next three children will be normal?arrow_forwardGregor Mendel’s basic principles of inheritance say that each trait is controlled by just one gene with just two alleles, and that each allele is clearly dominant or recessive to the other. However, we now know that many (if not most) traits are not actually inherited according to these rules. Name and describe two other (i.e., non-Mendelian) inheritance patterns, including how each one works, and a give specific example of an actual trait that follows each pattern.arrow_forwardA type of red-green colorblindness is inherited recessively on the X chromosome. A woman who is a carrier had children with a male that is not affected by the disease. Show your answers with the use of a Punnett square • What is the probability (% or likelihood) that a child is affected by the disease? • What is the probability (% or likelihood) that a son is a carrier? (Careful!) • Is there a chance that a girl of the couple is affected by the disease?arrow_forward
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