Biology: The Unity and Diversity of Life (MindTap Course List)
Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN: 9781305073951
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Chapter 31, Problem 3DAA

Cultured Skin for Healing Wounds Diabetes is a disorder in which the blood sugar level is not properly controlled. Among other effects, it reduces blood flow to the lower legs and feet. As a result, about 3 million diabetes patients have ulcers (open wounds that do not heal) on their feet. Each Year, about 80,000 require amputations.

Several companies provide cultured cell products designed to promote the healing of diabetic foot ulcers. FIGURE 31.21 shows the results of a clinical experiment that tested the effect of one such cultured skin product versus standard treatment for diabetic foot wounds. Patients were randomly assigned to either the experimental treatment group or the control group and their progress was monitored for 12 weeks.

Chapter 31, Problem 3DAA, Cultured Skin for Healing Wounds Diabetes is a disorder in which the blood sugar level is not

FIGUR E 31.21 Results of a multicenter study of the affects of standard treatment versus use of a cultured cell product for diabetic foot, ulcers. Bars show the percentage of foot ulcers that had completely heated.

3. How early was the healing difference between the control and treatment groups obvious?

Blurred answer
Students have asked these similar questions
Talk about a antibiotic that inhibits bacteria by inhibiting protein synthesis. Explain how these antibiotics interact with the protein synthesis machinery; what part of the protein synthesis machinery do they bind, and do all of these antibiotics bind to the same part of the machinery? How does this work to stop protein synthesis? Explain how it halts protein synthesis. Are these antibiotics bacteriostatic or bactericidal.  Why and what does that mean for therapy?
Throughout the semester we have seen that regulation is a key aspect of Biochemistry. It affects all aspects of the cell life cycle.  Choose 2(two) of the following and describe how “regulation” plays an important role.  NOTE:  We are not just talking about enzymatic control, but others levels of control too.  a. Committed/Pivotal steps in a metabolic pathway
Cancer cells treated with vitamin E succinate are generally more vulnerable to rupture of their lysosomal membranes (and subsequent apoptosis) than are normal cells, because: cancer cells often have an acidic cytosol, and their lysosomes have an acidic pH too cancer cells often have an acidic cytosol, but their lysosomes have an alkaline pH cancer cells often have an alkaline cytosol, and their lysosomes have an alkaline pH too cancer cells often have an alkaline cytosol, but their lysosomes have an acidic pH all of the above
Knowledge Booster
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • Exposing cells to which of the following drugs would inhibit the slow output response of a cell to a signaling ligandwithout having an effect on the fast output response ? A. Latrunculin - a molecule isolated from sponges, which binds near the nucleotide-binding cleft of monomericactin.B. Taxol - a molecule isolated from the bark of the pacific yew, which that stabilizes microtubules.C. Alpha-amanitin - a molecule isolated from deathcap mushrooms, which blocks RNA polymerase II.D. Phalloidin - a molecule isolated from deathcap mushrooms that stabilizes f-actin.E. Sodium orthovanadate - a molecule that inhibits alkaline and tyrosine phosphatases.
    Ca2+-ATPases are integral membrane proteins. They are active transport mechanisms that use the energy derived from ATP hydrolysis to pump calcium ions across the membrane. A specific form of Ca2+-ATPase, ERCA, is located on the endoplasmic reticulum membrane.  In which direction does ERCA transport calcium ions? a.) ERCA transports calcium ions from the lumen of the endoplasmic reticulum into the cytoplasm. b.) ERCA transports calcium ions from the cytoplasm into the lumen of the endoplasmic reticulum.
    Lactose transporter of E. coli is a well-studied proton driven cotransporter. It transports one lactose molecule together with one proton into the cell. Calculate the free energy change for transporting one more of protons into the cell? Membrane potential is -50 mV (inside is negative) and the pH = 7.2 inside the cell and the pH = 4.0 outside the cell. Temperature is 37 degrees celsius (310K). Remeber to convert pH to (H+) and express your answer as kJ/mol.
  • A. Fill in the blank: The motor protein responsible for transporting vesicles to the plasma membrane is named ____________. (spelling matters!) B. Specific inhibitors of dyneins have yet to be discovered. When they are discovered, how would they most likely affect cells?     Reduce retrograde transport of endosomes     Decrease pseudopod formation in amoeboid cells     Increase cell size     Decrease contraction of skeletal muscle
    Some cells in the pancreatic acinus form vesicles containing zymogens. Then the cells secrete the zymogens. Certain proteins called v-SNARES play a role in this process. What best describes the proteins called v-SNARES? a.) v-SNARES are proteins on the cytosolic face of the plasma membrane that help vesicles to fuse with the plasma membrane b.) v-SNARES are a type of glycosphingolipid in the vesicle lipid bilayer that help maintain vesicle integrity c.) v-SNARES are proteins on the surface of vesicles that help the vesicle fuse with the cytosolic face of the plasma membrane d.) v-SNARES are proteins contained inside of vesicles that help stabilize the vesicle contents until the vesicle fuses with the cytosolic face of the plasma membrane
    Why do cancer cells treated with vitamin E succinate appear to be more vulnerable to rupture of their lysosomal membranes (and subsequent apoptosis) than normal cells? cancer cells often have an alkaline cytosol, which destabilizes the alkaline lysosomes cancer cells often have an alkaline cytosol, which destabilizes the acidic lysosomes cancer cells often have an acidic cytosol, which destabilizes the alkaline lysosomes cancer cells often have an acidic cytosol, which destabilizes the acidic lysosomes all of the above
  • Liver cells proliferate excessively both in patients with chronic alcoholism and in patients with liver cancer. Is alcohol an anti-apoptopic compound?   2. Through diagrams with labeling and description, describe how signals such as taste and light are transmitted.
    Hurray! The bacteria did their job and expressed your protein. Now, you need to isolate biochemisfunase from the other bacterial proteins. To do this, you first need to break open the bacterial cells, a process called cell lysis. The lysis buffer you are going to use requires 225 mM potassium chloride (KCl), which is available as a crystalline solid. The lysis buffer also requires 22.5% (v/v) glycerol, which is available as a 100% stock solution. When making your lysis buffer,you added too much water,and you ended up with 375 ml of lysis buffer solution. The postdoc you are working with, underpaid and overworked, tells you to “rescue” the solution rather than remaking it. This same postdoc tells you that concentration is more important than the final volume. How would you go about rescuing the solution? (To make the required lysis buffer, take 56.25 mL of the 100% glycerol stock and add 193.75 mL water to it.)
    An adipocyteis an animal cell that is specialized for the storage of triacylglycerol molecules. A hepatocyteis far more metabolically active, spending nearly all its time synthesizing proteins and other materials to be used elsewhere in the body. Which cell would have more Golgi apparatus? Explain.
    • SEE MORE QUESTIONS
    Recommended textbooks for you
  • Human Physiology: From Cells to Systems (MindTap ...
    Biology
    ISBN:9781285866932
    Author:Lauralee Sherwood
    Publisher:Cengage Learning
  • Human Physiology: From Cells to Systems (MindTap ...
    Biology
    ISBN:9781285866932
    Author:Lauralee Sherwood
    Publisher:Cengage Learning
    The Cell Cycle and its Regulation; Author: Professor Dave Explains;https://www.youtube.com/watch?v=eqJqhA8HSJ0;License: Standard YouTube License, CC-BY
    Cell Division - Mitosis and Meiosis - GCSE Biology (9-1); Author: Mr Exham Biology;https://www.youtube.com/watch?v=w7vp_uRA8kw;License: Standard YouTube License, CC-BY