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Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892

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BuyFindarrow_forward

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892
Textbook Problem

Vasopressin is an important regulator of blood pressure. Taurinehas been shown to inhibit vasopressin release. An experiment was done to test the hypothesis that taurine acts as part of a negative feedback system that regulates vasopressin. The experiment measured the release of taurine from rat pituitary cells in the presence of vasopressin (10 nM) (Figure). Are these data consistent with the hypothesis? Why?

Chapter 38, Problem 1ITD, Vasopressin is an important regulator of blood pressure. Taurinehas been shown to inhibit

Source: L. Rosso et al. 2004. Vasopressin-induced taurine efflux from rat pituicytes: a potential negative feedback for hormone secretion. The Journal of Physiology 554:731–742.

Summary Introduction

To review:

Whether the given data are consistent with the fact that taurine exerts negative feedback on the release of vasopressin from the pituitary gland of the rat, and the reason behind the answer. The taurine released from pituitary gland over an hour, in the presence of vasopressin, is recorded in the following graph:

Biology: The Dynamic Science (MindTap Course List), Chapter 38, Problem 1ITD

Introduction:

The pituitary gland is a part of the endocrine system that releases regulatory hormones. The two parts of pituitary gland secrete different types of hormones, for example, the growth hormone, prolactin, corticotrophin, and others. The anterior part of the pituitary gland releases vasopressin and the oxytocin hormones, which are almost similar in length to amino acids.

Explanation

Vasopressin hormone regulates blood pressure by stimulating the kidney tubules to reabsorb water. It is also called as the antidiuretic hormone as it inhibits the loss of water through urine. A negative feedback loop is exerted by every hormone, once their function is achieved in the body.

For example, as the blood pressure is maintained inside the body then the vasopressin would send signals to the pituitary gland to inhibit its own release from the gland. Taurine is a chemical compound that inhibits the release of vasopressin. The data shown in the graph is consistent with the negative feedback loop exerted by taurine on the vasopressin release by the pituitary gland...

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