Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 38, Problem 1ITD
Summary Introduction

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Whether the given data are consistent with the fact that taurine exerts negative feedback on the release of vasopressin from the pituitary gland of the rat, and the reason behind the answer. The taurine released from pituitary gland over an hour, in the presence of vasopressin, is recorded in the following graph:

Biology: The Dynamic Science (MindTap Course List), Chapter 38, Problem 1ITD

Introduction:

The pituitary gland is a part of the endocrine system that releases regulatory hormones. The two parts of pituitary gland secrete different types of hormones, for example, the growth hormone, prolactin, corticotrophin, and others. The anterior part of the pituitary gland releases vasopressin and the oxytocin hormones, which are almost similar in length to amino acids.

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The peptide hormones vasopressin (ADH) and oxytocin each contain only nine amino acids.Vasopressin is an antidiuretic: even at low doses it controls the resorption of water by the distal tubules of the kidneys and regulates the osmotic content of blood. At high doses it can affect blood pressure. Oxytocin stimulates contraction of uterine smooth muscle. It is secreted during labor to effect delivery of the fetus. Oxytocin in therapeutically delivered to accelerate contractions in a labor that is not progressing. The primary sequences of the two peptides are shown below.Vasopressin: CYFQNCPRG    Oxytocin: CYIQNCPLGQuestions: 1. Draw the Primary Structure of Vasopressin and Oxytocin. 2. Calculate the overall charge of the peptides at pH 1, 7, 9, 11 and 14. Are the peptidespositively or negatively charged at pH 7? Between which pH values in this range are thepeptides neutral? Calculate the pI of each peptide. How might the differences affecttheir function?
In IBD1, if 20 mg of a drug is ultimately excreted unchanged into urine, the amount of the drug excreted unchanged into urine after 2 half-lives is _____ mg. Round the answer into the nearest integer.
What is an example ofpositive feedback of thehomeostatic regulation?
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