Concept explainers
To determine: The connection between the given data and the hypothesis based on starchy diet and AMY-1 gene duplication.
Introduction: An enzyme present in saliva that initiates or mediates the hydrolysis of starch into simpler sugar molecules is called as salivary amylase. AMY-1 is the gene that encodes for the enzyme salivary amylase. Humans possess this gene but the number of copies of that particular gene highly depends on dietary habits. Varied numbers of the copies of AMY1 genes are observed among people. The people consuming high-starch diets have more copies of the AMY1 gene when compared to people with low-starch diets.
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- Human Adaptation to a Starchy Diet The human AMY-1 gene encodes salivary amylase, an enzyme that breaks down starch. The number of copies of this gene varies, and people who have more copies generally make more enzyme. In addition, the average number of AMY-1 copies differs among cultural groups. George Perry and his colleagues hypothesized that duplications of the AMY-1 gene would be selectively advantageous in cultures in which starch is a large part of the diet. To test this hypothesis, the scientists compared the number of copies of the AMY-1 gene among members of seven cultural groups that differed in their traditional diets. FIGURE 39.16 shows their results. FIGURE 39.16 Number of copies of the AMY-1 gene among members of cultures with traditional high-starch or low-starch diets. The Hadza, Biaka, Mbuti, and Datog are tribes in Africa. The Yakut live in Siberia. 1. Starchy tubers are a mainstay of Hadza huntergatherers in Africa, whereas fishing sustains Siberia's Yakut. Almost 60 percent of Yakut had fewer than 5 copies of the AMY1 gene. What percentage of the Hadza had fewer than 5 copies?arrow_forwardHuman Adaptation to a Starchy Diet The human AMY-1 gene encodes salivary amylase, an enzyme that breaks down starch. The number of copies of this gene varies, and people who have more copies generally make more enzyme. In addition, the average number of AMY-1 copies differs among cultural groups. George Perry and his colleagues hypothesized that duplications of the AMY-1 gene would be selectively advantageous in cultures in which starch is a large part of the diet. To test this hypothesis, the scientists compared the number of copies of the AMY-1 gene among members of seven cultural groups that differed in their traditional diets. FIGURE 39.9 shows their results. FIGURE 39.9 Number of copies of the AMY-1 gene among members of cultures with traditional high-starch or low-starch diets. The Hadza, Biaka, Mbuti, and Datog are tribes in Africa. The Yakut live in Siberia. Do these data support the hypothesis that a starchy diet favors duplications of the AMY-1 gene?arrow_forwardThe human AMY-1 gene encodes salivary amylase, an enzyme that breaks down starch. The number of copies of this gene varies, and people who have more copies generally make more of the enzyme. In addition, the average number of AMY-1 copies differs among cultural groups. George Perry and his colleagues hypothesized that duplications of the AMY-1 gene would confer a selective advantage in cultures in which starch is a large part of the diet. To test this hypothesis, the scientists compared the number of copies of the AMY-1 gene among members of seven cultural groups that differed in their traditional diets. The Figure shows their results. Starchy tubers are a mainstay of Hadza hunter-gatherers in Africa, whereas fishing sustains Siberias Yakut. Almost 60% of Yakut had fewer than 5 copies of the AMY-1 gene. What percentage of the Hadza had fewer than 5 copies? FIGURENumber of copies of the AMY-1 gene among members of cultures with traditional high-starch or low-starch diets. Source: G. Perry et al. 2007. Diet and the evolution of human amylase gene copy number variation. Nature Genetics 39:12561260.arrow_forward
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