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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 4, Problem 11QP
Textbook Problem
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Analysis of Autosomal Recessive and Dominant Traits

Describe the primary gene or protein defect and the

resulting phenotype for the following diseases:

  1. a. cystic fibrosis
  2. b. Marfan syndrome

a.

Summary Introduction

To explain: The protein defect or primary gene and phenotype of cystic fibrosis.

Introduction: A genetic trait can be inherited in autosomal recessive pattern and autosomal dominant pattern. An autosomal dominant gene would express itself in homozygous dominant (AA) and heterozygous condition whereas an autosomal recessive gene would express itself only in homozygous recessive (aa) condition

Explanation of Solution

Cystic fibrosis:

Cystic fibrosis is caused by an impairment in the glands that synthesizes mucus, sweat, and digestive enzymes. In this condition, the thin mucous clogs which transport digestive enzym...

b.

Summary Introduction

To explain: The protein defect or primary gene and phenotype of marfan syndrome.

Introduction: A genetic trait can be inherited in autosomal recessive pattern and autosomal dominant pattern. An autosomal dominant gene would express itself in homozygous dominant (AA) and heterozygous condition whereas an autosomal recessive gene would express itself only in homozygous recessive (aa) condition.

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