Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 4, Problem 18QP
Analysis of Autosomal Recessive and Dominant Traits
Describe the
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Mutations of the CFTR gene causes ( Cerebral Plasy or Cystic Fibrosis or Craniofacial timbrosis or Fragile X syndrome). ? Which is (a/an) (Autosomal Dominant or X-linked ressessive or X-linked dominat or Recessive Deleterious)
Duchenne muscular dystrophy, which is inherited in an X-linked recessive pattern, nearly always occurs in males. Explain why.
Y-linked Inheritance. Holandric genes are inherited by males only.
Assuming that a man with hypertrichosis is married to a woman and they had children
1. what is the probability that his sons inherit the trait?
2. what is the probability that his daughters inherit the trait?
Chapter 4 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 4.3 - Does a pedigree drawn from the available...Ch. 4.3 - Prob. 2EGCh. 4.7 - Did the fact that Prince Albert and Queen Victoria...Ch. 4.7 - Which members of the pedigree could have been...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...
Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Use the following information to respond to the...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - A proband female with an unidentified disease...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Prob. 12QPCh. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 16QPCh. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 23QPCh. 4 - Prob. 24QPCh. 4 - Variations in Phenotype Expression Define...Ch. 4 - Prob. 26QPCh. 4 - Variations in Phenotype Expression A genetic...Ch. 4 - Variations in Phenotype Expression Explain how...
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- Analysis of X-Linked Dominant and Recessive Traits In the eighteenth century, a young boy with a skin condition known as ichthyosis hystrix gravior was identified. The phenotype of this disorder includes thickening of skin and the formation of loose spines that are sloughed off periodically. This man married and had six sons, all of whom had the same condition. He also had several daughters, all of whom were unaffected. In all succeeding generations, the condition was passed on from father to son. What can you theorize about the location of the gene that causes ichthyosis hystrix gravior?arrow_forwardAnalysis of Autosomal Recessive and Dominant Traits Describe the primary gene or protein defect and the resulting phenotype for the following diseases: a. cystic fibrosis b. Marfan syndromearrow_forwardAnalysis of X-Linked Dominant and Recessive Traits The following is a pedigree for a common genetic trait. Analyze the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linkedarrow_forward
- Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linkedarrow_forwardAnalysis of X-Linked Dominant and Recessive Traits A young boy is color-blind. His one brother and five sisters are not. The boy has three maternal uncles and four maternal aunts. None of his uncles children or grandchildren is color-blind. One of the maternal aunts married a color-blind man, and half of her children, both male and female, are color-blind. The other aunts married men who have normal color vision. All their daughters have normal vision, but half of their sons are color-blind. a. Which of the boys four grandparents transmitted the gene for color blindness? b. Are any of the boys aunts or uncles color-blind? c. Is either of the boys parents color-blind?arrow_forwardVariations in Phenotype Expression Define penetrance and expressivity.arrow_forward
- Analysis of Autosomal Recessive and Dominant Traits Does the indicated individual (III-5) show the trait in question?arrow_forwardTOPIC: Sex-linked inheritance Glucose-6-phosphate dehydrogenase deficiency/G6PDD (g) is an X-linked recessive condition wherein the red blood cells of affected individuals undergo premature hemolysis. Fragile X syndrome (F), on the other hand, is an X-linked dominant mutation characterized by a mild to moderate intellectual disability. Amelogenesis imperfecta (AMELY) (A) is a sex-linked congenital disorder affecting the formation of the teeth enamel making affected individuals at higher risk for dental cavities and related problems. Only male offspring inherit this condition. Jane is heterozygous for both X-linked traits like her mother. Her father is normal for both X-linked traits. James has a mother who suffers from G6PDD but not from fragile X-syndrome. His father does not exhibit any X-linked disorder but has amelogenesis imperfecta. What are the genotypes of the following: Jane: ________ James: _________ Jane’s mother: __________…arrow_forwardExplain why familial breast cancer shows a dominant pattern of inheritance in a pedigree even though it is recessive at the cellular level.arrow_forward
- Y-linked Amelogenesis imperfecta (A), a congenital disorder that affects the formation of the teeth enamel making affected individuals at higher risk for dental cavities and related problems. X-linked dominant hypophosphatemia (H), a form of rickets or vitamin D deficiency that affects the bones which causes pain, osteoarthritis, and abnormal shapeabnormal shape. X-linked recessive progressive Duchenne muscular dystrophy (m), a muscular disorder, leading to an irreversible gradual wasting of skeletal muscles. Hannah, the same as her mom, is heterozygous for both X-linked traits. While her dad is suffering from both muscular dystrophy and hypophosphatemia. Hannah's husband, Joey has a mom suffering from musculardystrophy regardless of having normal bone conditions. His dad has been blessed with strong muscles and bones, however, he is suffering from amelogenesis imperfecta. What are the complete genotypes of each person?a. Joey's momb. Joey's dadc. Joeyd. Hannah's mome. Hannah's dad f.…arrow_forwardBriefly explain the differences between somatic and germ line mutations. Also, tell us what kind of differences you expect to see between autosomal and X-linked mutations which lead to genetic disordersarrow_forwardModes of Inheritance for Single Gene Traits • Autosomal Dominant • Autosomal Recessive • X-linked Dominant • X-linked Recessive • Y-linked • Mitochondrial Let us assume that alleles for these traits follow complete dominance.arrow_forward
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