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Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linked

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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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Section
BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 4, Problem 21QP
Textbook Problem
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Analysis of X-Linked Dominant and Recessive Traits

As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as:

  1. a. autosomal dominant
  2. b. autosomal recessive
  3. c. X-linked dominant
  4. d. X-linked recessive
  5. e. Y-linked

Chapter 4, Problem 21QP, Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic

a.

Summary Introduction

To explain: The autosomal pattern of the inheritance of a trait according to the information given in the pedigree chart.

Introduction: A disease can be inherited into six patterns of inheritance: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked and mitochondrial inheritance. A pedigree chart is used to determine the pattern of the inheritance of disease.

Explanation of Solution

According to the pedigree analysis, in the first generation, I-1 and I-3 males are affected by the disease. I-3 has transmitted the disease to his son (II-2). This indicates that the pattern of inheritance of this disease can be autosomal dominant.

The disease condition is transmitted by II-2 to succeeding generations...

b.

Summary Introduction

To explain: The autosomal recessive pattern of inheritance according to the given pedigree chart.

Introduction: A disease can be inherited into six patterns of inheritance: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked and mitochondrial inheritance. A pedigree chart is used to determine the pattern of the inheritance of disease.

c.

Summary Introduction

To explain: The X-linked dominant pattern of the inheritance of disease according to the information given in the pedigree chart.

Introduction: A disease can be inherited into six patterns of inheritance: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked and mitochondrial inheritance. A pedigree chart is constructed on the basis of the family history of an individual.

d.

Summary Introduction

To explain: The X-linked recessive pattern of the inheritance of disease according to the information given in the pedigree chart.

Introduction: A disease can be inherited into six patterns of inheritance: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked and mitochondrial inheritance. A pedigree chart is constructed on the basis of the family history of an individual.

e.

Summary Introduction

To explain: The Y-linked pattern of the inheritance of disease according to the information given in the pedigree chart.

Introduction: A disease can be inherited into six patterns of inheritance: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked and mitochondrial inheritance. The pedigree chart is constructed on the basis of the family history of an individual.

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