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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 4, Problem 27QP
Textbook Problem
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Variations in Phenotype Expression

A genetic disorder characterized by falling asleep in genetics lectures is known to be 20% penetrant. All 90 students in a genetics class are homozygous for this gene. Theoretically, how many of the 90 students will fall asleep during the next lecture?

Summary Introduction

To explain: The number of students would fall asleep in the genetics lecture if the penetrance of this disorder is 20%.

Introduction: The probability of expression of the trait is called penetrance. It can also be defined as the probability of the expression of the disease phenotype, only when the genotype of disease is present. For example, if the penetrance of the gene is 100 %, then the dominant disorder has a mutant phenotype in all the individuals who carry defected alleles.

Explanation of Solution

It was found that the penetrance of a genetic disorder, which is characterized by falling asleep in the genetic lecture, is 20%. There are 90 students in the genetics class who are homozygous for this trait. Theoretically, the determination of the number of students who would fall asleep in the next lecture can be calculated by multiplying the penetrance with the total number of students in the class.

Studentssleeping=Penetrance×Total

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