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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 4, Problem 8QP
Textbook Problem
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Analysis of Autosomal Recessive and Dominant Traits

In the following pedigree, assume that the father of the proband is homozygous for a rare trait. What pattern of inheritance is consistent with this pedigree? In particular, explain the phenotype of the proband.

Chapter 4, Problem 8QP, Analysis of Autosomal Recessive and Dominant Traits In the following pedigree, assume that the

Summary Introduction

To explain: The pattern of inheritance that is consistent in the given pedigree chart.

Introduction: Pedigree analysis is the symbolic representation of the presence or absence of traits in a particular family. In the pedigree chart, a particular trait is represented by a particular symbol. It is used to determine the risk of a genetic disorder to an individual.

Explanation of Solution

The affected individual in the first generation is homozygous for the given trait which indicates that the disease would be either autosomal recessive or autosomal dominant. Moreover, the father cannot be homozygous for X-linked and Y-linked traits. In addition to this, the father cannot transmit the mitochondrial disease to the next generation...

Summary Introduction

To explain: The phenotype of the proband in the given pedigree chart.

Introduction: Pedigree analysis is the symbolic representation of the presence or absence of traits in a particular family. In the pedigree chart, the male is represented by square and the female is represented by a circle. The affected individual is represented by the shaded part. It is used to determine the risk of a genetic disorder to an individual.

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