Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 42, Problem 22CTQ
Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Suggest a reason for this.
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Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Explain relevant concepts in relation to tissue rejection in organ transplant.
Antibodies designed to interact with a specific antigensite are (monoclonal, polyclonal).
In regard to antigen presentation, MHC class I molecules usually present peptides derived from _____, whereas MHC class II molecules usually present peptides derived from _____.
a. intracellular cytosolic sources; vesicular system
b. phagolysosome; proteasomes
c. MIIC; self proteins
d. CLIP; HLA-DM
e. endocytic vesicles; endoplasmic reticulum.
Chapter 42 Solutions
Biology 2e
Ch. 42 - Figure 42.11 Which of the following statements...Ch. 42 - Figure 42.14 Based on what you know about MHC...Ch. 42 - Figure 42.16 The Rh antigen is found on Rh...Ch. 42 - Which of the following is a barrier against...Ch. 42 - Although interferons have several effects, they...Ch. 42 - Which organelle do phagocytes use to digest...Ch. 42 - Which innate immune system component uses MHC I...Ch. 42 - Which of the following is both a phagocyte and an...Ch. 42 - Which immune cells bind MHC molecules on APCs via...Ch. 42 - What “self” pattern is identified by NK cells?...
Ch. 42 - The acquired ability to prevent an unnecessary or...Ch. 42 - A memory B cell can differentiate upon reexposure...Ch. 42 - Foreign particles circulating in the blood are...Ch. 42 - The structure of an antibody is similar to the...Ch. 42 - The first antibody class to appear in the serum in...Ch. 42 - What is the most abundant antibody class detected...Ch. 42 - Breastfed infants typically are resistant to...Ch. 42 - Allergy to pollen is classified as: an autoimmune...Ch. 42 - A potential cause of acquired autoimmunity is...Ch. 42 - Autoantibodies are probably involved in: reactions...Ch. 42 - Which of the following diseases is not due to...Ch. 42 - Different MHC I molecules between donor and...Ch. 42 - If a series of genetic mutations prevented some,...Ch. 42 - Explain the difference between an epitope and an...Ch. 42 - What is a naïve B or T cell?Ch. 42 - How does the Th1 response differ from the Th2...Ch. 42 - In mammalian adaptive immune systems, T cell...Ch. 42 - How do B and T cells differ with respect to...Ch. 42 - Why is the immune response after reinfection much...Ch. 42 - What are the benefits and costs of antibody cross...
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- The Adaptive Immune Response Is a Specific Defense Against Infection Identify the components of cellular immunity, and define their roles in the immune response.arrow_forwardIf transplanting a solid organ such as a kidney, why is MHC II matching also important to success of the graft?arrow_forwardthe condition aplastic anemia is characterized by complete failure of the bone marrow to produce formed elements of the blood due to damaged hematopoietic stem cells. Explain how aplastic anemia would affect the inmune responsearrow_forward
- MHC class I molecules present peptide antigens derived from a(n) _______ compartment, whereas MHC class II molecules present peptide antigens derived from a(n) _______ compartment: a. extracellular; intracellular b. intracellular; extracellular c. opsonization; neutralization d. neutralization; opsonization e. none of the above.arrow_forwardDiscuss the role of autoantibodies in three named autoimmune diseases, then discuss how four named monoclonal antibody therapies (biologics) have been used to treat patients with autoimmunity. Use the aid of many diagrams. 2500 words.arrow_forwardWhich of the following interactions will NOT provoke an immune response? A. Endogenous antigen + MHC Class I + TCR + CD 8+ B. Exogenous antigen + MHC Class II + TCR + CD 4+ C. Exogenous antigen + MHC Class II + BCR D. Endogenous antigen + MHC Class I + BCRarrow_forward
- Explain the "antigen recognition by cells of adaptive immunity" in a simple way. Thank you, I will use this for infographics. NOTE: BULLET FORMarrow_forwardWhich of the following are TRUE of class I major histocompatibility complex (MHC) molecules? a. Class I MHC molecules present endogenous antigens. b. Class I MHC molecules are only present on erythrocyte surfaces. c. Class I MHC molecules bind complement. d. Class I MHC molecules present exogenous antigens.arrow_forwardIn your own personal understanding, why are complements important in cellular and humoral mediated immunity? please answer in a minimum of 5 sentences.arrow_forward
- Human immunodeficiency virus (HIV) preferentially destroys CD4+ cells. Specifically, what effect does this have on antibody and cell-mediated immunity? Please simple and original response. Thank you (:arrow_forwardDescribe the reason that it is useful that antibodies have two antigen binding arms.arrow_forwardMHC class II proteins: A. present exogenous antigen to the immune system B. both are found on antigen presenting cells and present exogenous C. antigen to the immune system are found on antigen presenting cellsarrow_forward
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