The rate of fractures in the two groups of children having osteogenesis imperfecta (OI). Introduction: Osteogenesis is a genetic disorder found in newborn babies also. The children suffering from OI are prone to bone damage. The child may be prone to bone fractures ranging from four to five to hundreds of fractures per year based on the level of intensity of the disease. This disease can respond to certain drug treatments and the damage of the bones can be slowed down causing a reduced number of fractures per year.

Question

Want to see the full answer?

Answer 1

Question

Chapter 43, Problem 3ITD

Summary Introduction

To review:

The rate of fractures in the two groups of children having osteogenesis imperfecta (OI).

Introduction:

Osteogenesis is a genetic disorder found in newborn babies also. The children suffering from OI are prone to bone damage. The child may be prone to bone fractures ranging from four to five to hundreds of fractures per year based on the level of intensity of the disease. This disease can respond to certain drug treatments and the damage of the bones can be slowed down causing a reduced number of fractures per year.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

In this type of ossification mesenchymal cells in the embryonic skeleton gather together and begin to differentiate into specialized cells that form a template of the future bone. Ossification of flat bones begins as mesenchymal cells form a template of the future bone. They then differentiate into osteoblasts at the ossification center. Osteoblasts secrete the extracellular matrix and deposit calcium, which hardens the matrix. The non-mineralized portion of the bone or osteoid continues to form around blood vessels, forming spongy bone. Connective tissue in the matrix differentiates into red bone marrow in the fetus. The spongy bone is remodeled into a thin layer of compact bone on the surface of the spongy bone. The process depicted in the description above and on this slide is (check all that apply):

In this type of ossification mesenchymal cells in the embryonic skeleton gather together and begin to differentiate into specialized cells that form a template of the future bone. Ossification of flat bones begins as mesenchymal cells form a template of the future bone. They then differentiate into osteoblasts at the ossification center. Osteoblasts secrete the extracellular matrix and deposit calcium, which hardens the matrix. The non-mineralized portion of the bone or osteoid continues to form around blood vessels, forming spongy bone. Connective tissue in the matrix differentiates into red bone marrow in the fetus. The spongy bone is remodeled into a thin layer of compact bone on the surface of the spongy bone. The process depicted in the description above and on this slide is (check all that apply): intermembranous ossification endomembrane ossification intramembranous ossification red bone marrow formation

Bisphosphonates are a class of medications that treat osteoporosis by slowing the breakdown of bone. What type of cells do bisphosphonates target? A. Osteoclasts B. Mesenchymal stem cells C. Osteocytes D. Osteoblasts