Textbook Problem

Space, the final frontier! Indeed, but being in space causes some problems. Astronauts in space show a decline in their ability to mount an immune response and, consequently, develop a decreased resistance to infection. Two potentially important differences in physiology in space versus on Earth are more fluid flowing to the head and a lack of weight bearing on the lower limbs. Could they be involved somehow in the deleterious effect on the immune system? Design an experiment to be done on Earth to answer this question.