BIOLOGY(LL)-W/ACCESS CODE >CUSTOM<
BIOLOGY(LL)-W/ACCESS CODE >CUSTOM<
12th Edition
ISBN: 9781264058167
Author: Raven
Publisher: MCG CUSTOM
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Chapter 45, Problem 2A

You have identified a calcium storage disease in rats. How would this inability to store Ca2+ affect muscle contraction?

a. Ca2+ would be unable to bind to tropomyosin, which enables troponin to move and reveal binding sites for cross-bridges.

b. Ca2+ would be unable to bind to troponin, which enables tropomyosin to move and reveal binding sites for cross-bridges.

c. Ca2+ would be unable to bind to tropomyosin, which enables troponin to release ATP.

d. Ca2+ would be unable to bind to troponin, which enables tropomyosin to release ATP.

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What event causes a troponin-tropomyosin complex to regain its original shape in muscle relaxation? a. stimulation of ACh receptors b. diffusion of Na+ back into transverse tubules c. return of Ca2+ into the sarcoplasmic reticulum d. breaking of the bond with tropomyosin
Muscle contraction is the result of critical steps characterized by conformational changes to protein structures in the supramolecule. Which of the following conformational changes requires energy, i.e. ATP hydrolysis? A. Binding of calcium to tropomyosin changing its conformation and exposing a binding site in troponin B. Binding of myosin to troponin resulting in the power stroke and cross-bridge cycle of muscle contraction. C. Disruption in the binding of the myosin head to troponin preceding its release and relaxation back to its activated form. D. Binding of ATP to the myosin head bound to troponin.
With regard to muscle contraction, which of the following is an INCORRECT statement with regard to the interactions of filaments that occur in the sarcomere? A. When muscles are relaxed tropomyosin blocks binding sites on actin subunits, which keeps cross-bridges from forming. B. The myosin heads conduct a power stroke motion to slide when bound to actin, to move the "thin" filaments towards the center of the sarcomere. C. During contraction, actin subunits are removed from the ends of the "thin" filaments to shorten actin polymers, thus reducing the length of the sarcomere. D. "Thick" filaments are anchored at the M-line, while "thin" filaments are anchored at the Z-line. E. Numerous myosin heads engage with the actin filaments simultaneously, such that there is no back-slipping during the contraction process.
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