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Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892

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BuyFindarrow_forward

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892
Textbook Problem

The human AMY-1 gene encodes salivary amylase, an enzyme that breaks down starch. The number of copies of this gene varies, and people who have more copies generally make more of the enzyme. In addition, the average number of AMY-1 copies differs among cultural groups.

George Perry and his colleagues hypothesized that duplications of the AMY-1 gene would confer a selective advantage in cultures in which starch is a large part of the diet. To test this hypothesis, the scientists compared the number of copies of the AMY-1 gene among members of seven cultural groups that differed in their traditional diets. The Figure shows their results.

Do these data support the hypothesis that a starchy diet favors duplications of the AMY-1 gene?

Chapter 47, Problem 3ITD, The human AMY-1 gene encodes salivary amylase, an enzyme that breaks down starch. The number of

FIGURE Number of copies of the AMY-1 gene among members of cultures with traditional high-starch or low-starch diets.

Source: G. Perry et al. 2007. Diet and the evolution of human amylase gene copy number variation. Nature Genetics 39:1256–1260.

Summary Introduction

To review:

Whether the data support the hypothesis put forward by George Perry and his team about the duplication of AMY-1 genes and its selective advantage in cultures having starch as their base diet.

Introduction:

George Perry and his team conducted experiments on the AMY-1 gene that could confer a selective advantage in cultures in which starch is a large part of the diet. They hypothesized that duplication of the gene would have a selective advantage. They collected data based on seven different cultural groups with different traditional diets.

Explanation

The graph given below represents the number of AMY-1 gene copies among the different members of the culture in comparison to the traditional low-starch diet and high-starch diet:

In the human body, amylase enzymes are produced in the saliva of the mouth or pancreas...

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