Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter 5, Problem 16PDQ
In Drosophila, Dichaete (D) is a mutation on chromosome III with a dominant effect on wing shape. It is lethal when homozygous. The genes ebony body (e) and pink eye (p) are recessive mutations on chromosome III. Flies from a Dichaete stock were crossed to homozygous ebony, pink flies, and the F1 progeny, with a Dichaete
- (a) Diagram this cross, showing the genotypes of the parents and offspring of both crosses.
- (b) What is the sequence and interlocus distance between these three genes?
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In Drosophila, Dichaete (D) is a mutation on chromosome III with a dominant effect on wing shape. It is lethal when homozygous. The genes ebony body (e) and pink eye (p) are recessive mutations on chromosome III. Flies from a Dichaete stock were crossed to homozygous ebony, pink flies, and the F1 progeny, with a Dichaete phenotype, were backcrossed to the ebony, pink homozygotes. Using the results of this backcross shown in the table,
(b) What is the sequence and inter locus distance between these three genes?
In Drosophila, Dichaete (D) is a mutation on chromosome III with a dominant effect on wing shape. It is lethal when homozygous. The genes ebony body (e) and pink eye (p) are recessive mutations on chromosome III. Flies from a Dichaete stock were crossed to homozygous ebony, pink flies, and the F1 progeny, with a Dichaete phenotype, were backcrossed to the ebony, pink homozygotes. Using the results of this backcross shown in the table,
(a) Diagram this cross, showing the genotypes of the parents and offspring of both crosses.
(b) What is the sequence and inter locus distance between these three genes?
In the fruit fly, dumpy wings (d) and purple eyes (p) are encoded by mutant alleles that are recessive to those that produce wild type traits; long wings (d+) and red eyes (p+). These two genes are on the same chromosome. In a particular lab, two researchers Walt and Jesse crossed a fly homozygous for dumpy wings and purple eyes with a fly homozygous for the wild type traits. The F1 progeny, which had long wings and red eyes, was then crossed with flies that had dumpy wings and purple eyes. Unfortunately, the progeny of this cross somehow escaped. To prevent their other projects from contamination, they decided to spend an exceptionally boring hour in the lab catching and counting the progeny and found the following:
long wings, red eyes – 482
dumpy wings, purple eyes – 473
long wings, purple eyes – 23
dumpy wings, red eyes - 22
What is the genetic distance between these two loci?
a. 4.5 cM
b. 55 cM
c. 45 cM
d. 49.5 cM
e. 4.7 cM
Chapter 5 Solutions
Concepts of Genetics (12th Edition)
Ch. 5 - In a family with one autistic child the risk for...Ch. 5 - Given that the prenatal test can provide only a...Ch. 5 - Consider two hypothetical recessive autosomal...Ch. 5 - With two pairs of genes involved (P/p and Z/z), a...Ch. 5 - In Drosophila, a heterozygous female for the...Ch. 5 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 5 - Review the Chapter Concepts list on page 94. Most...Ch. 5 - Describe the cytological observation that suggests...Ch. 5 - Why does more crossing over occur between two...Ch. 5 - Explain why a 50 percent recovery of...
Ch. 5 - Why are double-crossover events expected less...Ch. 5 - What is the proposed basis for positive...Ch. 5 - What two essential criteria must be met in order...Ch. 5 - The genes dumpy (dp), clot (cl), and apterous (ap)...Ch. 5 - Colored aleurone in the kernels of com is due to...Ch. 5 - In the cross shown here, involving two linked...Ch. 5 - In a series of two-point mapping crosses involving...Ch. 5 - Two different female Drosophila were isolated,...Ch. 5 - In Drosophila, a cross was made between femalesall...Ch. 5 - Another cross in Drosophila involved the...Ch. 5 - In Drosophila, Dichaete (D) is a mutation on...Ch. 5 - Drosophila females homozygous for the third...Ch. 5 - In Drosophila, two mutations, Stubble (Sb) and...Ch. 5 - If the cross described in Problem 18 were made,...Ch. 5 - Are mitotic recombinations and sister chromatid...Ch. 5 - What possible conclusions can be drawn from the...Ch. 5 - An organism of the genotype AaBbCc was testcrossed...Ch. 5 - Based on our discussion of the potential...Ch. 5 - Traditional gene mapping has been applied...Ch. 5 - DNA markers have greatly enhanced the mapping of...Ch. 5 - In a certain plant, fruit is either red or yellow,...Ch. 5 - Two plants in a cross were each heterozygous for...Ch. 5 - A number of humanmouse somatic cell hybrid clones...Ch. 5 - A female of genotype produces 100 meiotic tetrads....Ch. 5 - In laboratory class, a genetics student was...Ch. 5 - Drosophila melanogaster has one pair of sex...Ch. 5 - In Drosophila, a female fly is heterozygous for...Ch. 5 - The gene controlling the Xg blood group alleles...Ch. 5 - Prob. 34ESP
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- Sepia eyes, spineless bristles, and striped body are three recessive mutations in Drosophila found on chromosome 3. A genetics student crosses a fly homozygous for the alleles encoding sepia eyes, spineless bristles, and striped body with a fly homozygous for the wild-type alleles—encoding red eyes, normal bristles, and solid body. The female progeny are then test-crossed with males that have sepia eyes, spineless bristles, and striped body. Assume that the interference between these genes is 0.2 and that 400 progeny flies are produced by the testcross. Based on the map distances provided in Figure , predict the phenotypes and proportions of the progeny resulting from the test cross.arrow_forwardOne of the X chromosomes in a particular Drosophila female had a normal order of genes but carried recessive alleles of the genes for yellow body color (y), vermilion eye color (v), and forked bristles (f), as well as the dominant X-linked Bar eye mutation (B). Her other X chromosome carried the wild-type alleles of all four genes, but the region including y+, v+, and f+ (but not B+) was inverted with respect to the normal order of genes. This female was crossed to a wild- type male in the cross diagrammed her. The cross produced the following male offspring:* table in figure a. Why are there no male offspring with the allele combinations y v f+, v+ v+ f, y v+ f+, or y+ v f (regardless of the allele of the Bar eye gene)?b. What kinds of crossovers produced the y v f b+ and v+ y+ f+ B offspring? Can you determine any genetic distances from these classed of progeny?c. What kinds of crossovers produced the y+ v f+ B+ and y v+ f B offspring?arrow_forwardOne of the X chromosomes in a particular Drosophila female had a normal order of genes but carried recessive alleles of the genes for yellow body color (y), vermilion eye color (v), and forked bristles (f), as well as the dominant X-linked Bar eye mutation (B). Her other X chromosome carried the wild-type alleles of all four genes, but the region including y+, v+, and f+ (but not B+) was inverted with respect to the normal order of genes. This female was crossed to a wild-type male in the cross diagrammed her. The cross produced the following male offspring: Y v f B 48 y+ v+ f+ B+ 45 y v f B+ 11 y+ v+ f+ B 8 y v f B 1 y+ v+ f+ B+ 1 a. Why are there no male offspring with the allele combinations y v f+, v+ v+ f, y v+ f+, or y+ v f (regardless of the allele of the Bar eye gene)? b.What kinds of crossovers produced the y v f b+ and v+ y+ f+ B offspring? Can you determine any genetic distances from these classed of progeny? c. What kinds of crossovers produced the…arrow_forward
- The mutant genes for vestigial wings and singed bristles are approximately 30 map units apart on chromosome II in Drosophila. Assume that a vestigial-winged female was mated to a singed-bristle male, and that the resulting F1 phenotypically wild type females were mated to vestigial singed males. Of 1000 offspring, which phenotype class would represent the product of crossing over between the genes, and how many would you expect? a) vestigial, 300 flies b) vestigial, 150 flies wild type, 300 flies d) singed, 150 flies e) vestigial, singed double mutants, 150 fliesarrow_forwardIn the fruit fly Drosophila melanogaster, the trait of black body is due to a gene on chromosome 2 and black body b is recessive to wild type body b + . The trait of purple eyes is controlled by a gene that is also on chromosome 2 and purple eyes p is recessive to wild type eyes p + . A true-breeding wild type strain is crossed with a true breeding strain that has black bodies and purple eyes. The F1 generation is then testcrossed to the black body, purple eye strain and 500 progeny are produced as follows: 224 wild type for both body and eye 236 black body and purple eye 18 wild type body and purple eye 22 black body and wild type eye. What is the recombination frequency and genetic map distance between the two genes?arrow_forwardIn Drosophila, the vermilion eye color is determined by a recessive allele, v, of an X-linked gene. The wildtype color is determined by the v+ allele and causes a brick red eye color. In a cross of a heterozygous female with a wild type male you observe 340 red eye females, 136 red eye males, and 90 vermillion males. Do these results follow your expectations?arrow_forward
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