Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 5, Problem 6P

In Drosophila, the map positions of genes are given in mapunits numbering from one end of a chromosome to theother. The X chromosome of Drosophila is 66 m .u . long.The X-linked gene for body color with two alleles, y+ forgray body and y for yellow body resides at one end ofthe chromosome at map position 0 .0 . A nearby locus foreye color, with alleles w+ for red eye and w for white eye, is located at map position 1 .5 . A third X-linked gene, controlling bristle form, with f+ for normal bristles and f forforked bristles, is located at map position 56 .7 . Each generesides on the X chromosome, and at each locus the wildtype allele is dominant over the mutant allele.

a. In a cross involving these three X-linked genes, do youexpect any gene pair(s) to show genetic linkage? Explainyour reasoning.

b. Do you expect any of these gene pair(s) to assort independently? Explain your reasoning.

c. A wild - type female fruit fly with the genotype y+w+f/ ywf+ is crossed to a male fruit fly that has yellow body, white eye, and forked bristles. Predict the frequency of each progeny phenotype class produced by this mating

d. Explain how each of the predicted progeny classes isproduced.

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. In Drosophila, three loci, Bar eyes (B, dominant), Scalloped wings (sd, recessive), and tanbody (t, recessive) are all located on the X chromosome. Bar eyes is located at position57, scalloped wings at position 51.5, and tan body at position 27.5. A female whosemother was homozygous dominant at all three loci and whose father was hemizygousrecessive at all three loci produces 1000 egg cells. How many TsdB cells would youexpect if chromosomal interference = 0? ____6-7_______ why is that the answer?
The recessive, X-linked z1mutation of the Drosophilagene zeste (z) can produce a yellow (zeste) eye coloronly in flies that have two or more copies of the wildtype white (w) gene. Using this property, tandem duplications of the w+ gene called w+Rwere identified.Males with the genotype y+ z1w+R spl+ / Y thus havezeste eyes. These males were crossed to females withthe genotype y z1 w+R spl / y+ z1 w+R spl+. (These fourgenes are closely linked on the X chromosome, in theorder given in the genotype, with the centromere tothe right of all these genes: y = yellow bodies; y+ =tan bodies; spl = split bristles; spl+ = normal bristles.) Out of 81,540 male progeny of these females,the following exceptions were found:Class A 2430 yellow bodies, zeste eyes, wild-type bristlesClass B 2394 tan bodies, zeste eyes, split bristlesClass C 23 yellow bodies, wild-type eyes, wild-type bristlesClass D 22 tan bodies, wild-type eyes, split bristlesa. What were the phenotypes of the remainder of the81,540 males…
In Drosophila, a cross was made between females expressing thethree X-linked recessive traits, scute bristles (sc), sable body (s),and vermilion eyes (v), and wild-type males. All females were wildtype in the F1, while all males expressed all three mutant traits.The cross was carried to the F2 generation and 1000 offspringwere counted, with the results shown in the following table. Nodetermination of sex was made in the F2 data. Question:Calculate the coefficient of coincidence; does this represent positive or negative interference? Phenotype Offspringsc s v                314+ + +               280+ s v                150sc + +             156sc + v               46+ s +                30sc s +               10+ + v                14

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Genetic Analysis: An Integrated Approach (3rd Edition)

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