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Organic And Biological Chemistry

7th Edition
STOKER + 1 other
ISBN: 9781305081079

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Section
BuyFindarrow_forward

Organic And Biological Chemistry

7th Edition
STOKER + 1 other
ISBN: 9781305081079
Textbook Problem

Which of the following physiologically active amines functions as both a neurotransmitter and a central nervous system stimulant?

  1. a. serotonin
  2. b. dopamine
  3. c. norepinephrine
  4. d. no correct response

Interpretation Introduction

Interpretation:

Among the given physiologically active amines, the one that has function as both central nervous system stimulant and neurotransmitter has to be chosen from the given options.

Concept Introduction:

Generally amines are toxic in nature.  If a compound contains only amine as its functional group, they will be often toxic.  Due to this, in biological systems they are not prevalent.  If the same compound contains more than one functional group apart from amine means it can be physiologically active.  Important “core” structures that are frequently encountered in polyfunctional amines that have biological effects are tryptamine core and phenethylamine core.

Organic And Biological Chemistry, Chapter 6.10, Problem 2QQ

There are three types of effects that an amine can exert.  They are neurotransmitters, central nervous system stimulants and decongestants.  Neurotransmitters are the substances that are present in human body that help in passing impulse of nerves from one cell to another.  Central nervous stimulants are the substances that help in speeding up of physical and mental processes.  Decongestant is a substance that is used to relieve nasal congestion.

Explanation

Reason for correct option:

Polyfunctional amines have biological activity.  Some of the compounds exhibit more than one biological activity.  Structure of norepinephrine is,

This compound can act both as neutrotransmitter and central nervous system stimulant.

Hence, option (c) is a correct one.

Reason for incorrect option:

Option (a) tells that the serotonin can acts as both neurotransmitter and central nervous system stimulant...

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