(a)
Interpretation:
The configuration of the chiral center must be assigned to the substrate.
Concept Introduction :
The absolute configuration of a chiral center depends on the nature of substituents. The absolute configuration is determined using CIP (Cahn-Ingold-Prelog) priority rule according to which priority of a group is higher if the
(b)
Interpretation:
The configuration of the chiral center must be assigned in the product.
Concept Introduction :
The absolute configuration of a chiral center depends on the nature of substituents. The absolute configuration is determined using CIP (Cahn-Ingold-Prelog) priority rule according to which priority of a group is higher if atomic number is higher.
(c)
Interpretation:
Whether the given SN2 reaction proceeds with inversion of configuration must be explained.
Concept Introduction :
The SN2 reaction involves back side attack of the nucleophile which results in inversion of configuration.
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ORGANIC CHEMISTRY-PRINT COMPANION (LL)
- Please indicate the correct stereochemistry for each chiral center in the product.arrow_forwardD How many Chiral centers are in the product of the quen reaction? HBr ROOR 8) What is the product of the qiven reaction? он 1. BH3 Oн 2. HyOz, HzO, NGOH HOH こニarrow_forward2. In aqueous solution d-glucose (or dextrose) exists in equilibrium between a linear and cyclic form shown below. A. Mark all the stereocenters in the linear form of the molecule. Number them 1,2,3, etc. B. Draw out the reaction that converts the linear form to the 6-membered ring using the arrow formalism. C. Identify the stereocenters in the 6-member ring that correspond to the stereocenters in the linear form marking them as 1,2,3, etc. The reaction also created a new stereocenter. Mark it as H -OH HO--H H--OH нон Ho но HO HO H он H-OH H но.arrow_forward
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- 1. Ketones react with sodium acetylide (the sodium salt of acetylene, Na“:C=CH) to give alcohols. For example: OH 2 H;0 a. Is the product chiral? b. Draw both major and minor reaction products, assuming that the reaction takes place preferentially from the Re face of the carbonyl group. Is the product mixture optically active? Explain.arrow_forwardWhich statement best describes the nature of the product(s) formed in this reac O A 1. Hg(OAc)2, H₂O 2. NaBH4 A. They are a pair of diastereomers. B. They are a pair of enantiomers. C. It is a single, achiral product. D. It is a single, chiral product. OD ? Question 34arrow_forwardA 0.26 M solution of an enantiomerically pure chiral compound D has an observed rotation of +0.197° in a 1‑dm sample container. The molar mass of the compound is 132.3 g/mol. a. What is the specific rotation of D? b. What is the observed rotation if this solution is mixed with an equal volume of a solution that is 0.26 M in L, the enantiomer of D? c. What is the observed rotation if the solution of D is diluted with an equal volume of solvent?arrow_forward
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