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How does DNA replication occur in a precise manner to ensure that identical genetic information is put into the new chromatid? See Figures 8.12 and 8.13. FIGURE 8.12 In DNA replication, the two polynucleotide strands uncoil, and each is a template for synthesizing a new strand. A replicated DNA molecule contains one new strand and one old strand. This mechanism is called semiconservative replication. FIGURE 8.13 A close-up look at the process of DNA replication. (a) As the strands uncoil, bases are added to the newly synthesized strand by complementary base pairing with bases in the template strand. The new bases are linked together by DNA polymerase. (b) DNA synthesis can proceed only in the 5′ →3′ direction; newly synthesized DNA on one template strand is made in short segments and linked together by the enzyme DNA ligase.

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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 8, Problem 23QP
Textbook Problem
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How does DNA replication occur in a precise manner to ensure that identical genetic information is put into the new chromatid? See Figures 8.12 and 8.13.

Chapter 8, Problem 23QP, How does DNA replication occur in a precise manner to ensure that identical genetic information is , example  1

FIGURE 8.12 In DNA replication, the two polynucleotide strands uncoil, and each is a template for synthesizing a new strand. A replicated DNA molecule contains one new strand and one old strand. This mechanism is called semiconservative replication.

Chapter 8, Problem 23QP, How does DNA replication occur in a precise manner to ensure that identical genetic information is , example  2

FIGURE 8.13 A close-up look at the process of DNA replication. (a) As the strands uncoil, bases are added to the newly synthesized strand by complementary base pairing with bases in the template strand. The new bases are linked together by DNA polymerase. (b) DNA synthesis can proceed only in the 5′ →3′ direction; newly synthesized DNA on one template strand is made in short segments and linked together by the enzyme DNA ligase.

Summary Introduction

To determine: The process of DNA replication that occurs in a precise manner to ensure that identical genetic information is put into the new chromatid.

Introduction: DNA must be copied before the process of cell division so as to obtain the same copy of genetic information that will pass on to each daughter cell. DNA replication occurs from bacteria to humans. DNA replication is completely dependent on complementary base pairing in polynucleotide chains of DNA. The process of DNA replication is also known as ‘semiconservative replication’ because in each new complementary DNA, one old strand is conserved and one new strand is synthesized.

Explanation of Solution

DNA replication is a multistep complex process which occurs in each living thing. DNA replication occurs in the S phase of the cell cycle. The double helix structure of DNA is first unwounded by breaking of hydrogen bonds between two strands. Once strands get separated DNA polymerase reads the nucleotide sequences and adds new complementary sequences in 5 to 3 direction. The new nucleotide sequences link with template strand to form a complementary strand.

The newly added polynucleotide chain moves along with template DNA and DNA polymerase reads the newly synthesized sequence. DNA polymerase removes any incorrect base pairing and adds the correct ones

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