Campbell Essential Biology (6th Edition) - standalone book
Campbell Essential Biology (6th Edition) - standalone book
6th Edition
ISBN: 9780133917789
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece, Kelly A. Hogan
Publisher: PEARSON
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Chapter 9, Problem 21BS

Gregor Mendel never saw a gene, yet he concluded that some inherited factors were responsible for the patterns of inheritance he observed in peas. Similarly maps of Drosophila chromosomes (and the very idea that genes are carried on chromosomes) were conceived by observing the patterns of inheritance of linked genes, not by observing the genes directly. Is it legitimate for biologists to claim the existence of objects and processes they cannot actually see? How do scientists know whether an explanation is correct?

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Gregor Mendel never saw a gene, yet he concluded that some inherited factors were responsible for the patterns of inheritance he observed in peas. Similarly maps of Drosophila chroma zones were conceived by observing the patterns of inheritance of linked genes, not by observing the genes directly. Is it legitimate for biologists to claim the existence of objects and processes they cannot actually see? How do scientists know whether an explanation is correct?
In your own words, define the terms “orthologous” and “paralogous” genes. Then, briefly suggest by what mechanism, during evolution, each of these homologous gene types is most likely to have arisen.
You are working in the lab with strains of Drosophila that have either normal legs or abnormally short legs and you are studying the gene responsible. You know that normal legs are dominant to short legs. You come across a misplaced fly with normal legs, but you are not sure of his genetic background and you want to keep him in your experiments. (Without doing a molecular analysis), How could you figure out whether he was heterozygous or homozygous for the leg gene that you are studying? (Describe what you would do and how the results would answer the question.) What is the procedure you described above called?
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