Cardiopulmonary Anatomy & Physiolo...

7th Edition
Des Jardins + 1 other
ISBN: 9781337794909



Cardiopulmonary Anatomy & Physiolo...

7th Edition
Des Jardins + 1 other
ISBN: 9781337794909
Textbook Problem

Which of the following has the most powerful effect on the respiratory components of the medulla?

A. Decreased O2

B. Increased H+

C. Decreased CO2

D. Increased pH

Summary Introduction


There are specific neuron areas located within the pons and medulla oblongata of the brain that regulate the rhythmicity of respiration. These areas are responsible for adjusting the ventilator pattern by inhibiting, stimulating, and monitoring them. Specific ventilators are activated by medullary centers. The major areas which send information for the activation of ventilators are the central chemoreceptors and peripheral chemoreceptors.


Justification for the correct answer:

Option (B) is, ‘increased H+.’ This option is correct, as hydrogen ions are present in the cerebrospinal fluid. The central chemoreceptors regulate the concentration of the hydrogen ions. The blood-brain barrier is impermeable to hydrogen ions and bicarbonate ions. Thus, increased hydrogen ion concentration leads to reduced pH (potential of hydrogen). When the cerebrospinal fluid has inefficient buffering capacity, a high concentration of hydrogen ions causes the alveolar ventilation to increase. Hence, option (B) is the correct answer.

Justification for the incorrect answers:

Option (A) is, ‘decreased O2 (oxygen)...

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