Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 9, Problem 31P
Interpretation Introduction

Interpretation:

The way by which the primary structure of the Walker A region of P-glycoprotein facilitates ATP binding is to be stated.

Concept introduction:

One of the largest protein groups is the ATP binding cassette superfamily of proteins. P-glycoprotein, a member of this family acts as an efflux pump and works as a multidrug transporter to removes xenobiotics from the cytosol of the cell. These xenobiotics consist of cellular debris, toxins and helpful amphipathic drugs.

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