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BiochemistryBiochemistry9th Edition
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RECALL What is RNA interference?

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Biochemistry

9th Edition
Mary K. Campbell + 2 others
Publisher: Cengage Learning
ISBN: 9781305961135

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BuyFindarrow_forward

Biochemistry

9th Edition
Mary K. Campbell + 2 others
Publisher: Cengage Learning
ISBN: 9781305961135
Chapter 9, Problem 56RE
Textbook Problem
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RECALL What is RNA interference?

Interpretation Introduction

Interpretation:

The definition of RNA interference.

Concept Introduction:

The process of RNAi (ribonucleic acid interference) was a breakthrough in the year 2002 and the phenomenon was published in Science magazine.

There are certain short stretches of RNA (20-30 nucleotides) that are found to have enormous control over the expression of a gene.

Explanation of Solution

RNA interference is a biological process that involves the inhibition of gene expression with the help of an RNA molecule only. This process is a protection mechanism in many species, in which the siRNA is used to eliminate the expression of an undesirable gene. Examples of such genes can include a gene that is causing an uncontrolled growth or a gene that comes from a virus or bacteria. RNA interference is also known by other names, like co-suppression, post-transcriptional gene silencing (PTGS) and quelling.

There are two types of RNA that are involved in RNA interference - siRNA (small interfering RNA) and miRNA (micro RNA)...

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Ch. 9 - REFLECT AND APPLY Consider the following in light...Ch. 9 - RECALL What is the structural difference between...Ch. 9 - RECALL What is the structural difference between...Ch. 9 - RECALL Give the name of the base, the...Ch. 9 - RECALL What is the difference between ATP and...Ch. 9 - RECALL Give the sequence on the opposite strand...Ch. 9 - RECALL Are the sequences shown in Question 6 those...Ch. 9 - REFLECT AND APPLY (a) Is it biologically...Ch. 9 - REFLECT AND APPLY A friend tells you that only...Ch. 9 - REFLECT AND APPLY In the early days of molecular...
Ch. 9 - REFLECT AND APPLY Why is RNA more vulnerable to...Ch. 9 - RECALL In what naturally occurring nucleic acids...Ch. 9 - RECALL Draw a GC base pair. Draw an AT base pair.Ch. 9 - RECALL Which of the following statements is (are)...Ch. 9 - BIOCHEMICAL CONNECTIONS What are the two principal...Ch. 9 - BIOCHEMICAL CONNECTIONS Describe the landmark case...Ch. 9 - BIOCHEMICAL CONNECTIONS What two genes are at the...Ch. 9 - RECALL How do the major and minor grooves in B-DNA...Ch. 9 - RECALL Which of the following statements is (are)...Ch. 9 - RECALL Define supercoiling, positive supercoil,...Ch. 9 - RECALL What is propeller twist?Ch. 9 - RECALL What is an AG/CT step?Ch. 9 - RECALL Why does propeller-twist occur?Ch. 9 - RECALL What is the difference between B-DNA and...Ch. 9 - RECALL If circular B-DNA is positively...Ch. 9 - RECALL Briefly describe the structure of...Ch. 9 - BIOCHEMICAL CONNECTIONS What is the motive behind...Ch. 9 - REFLECT AND APPLY List three mechanisms that relax...Ch. 9 - REFLECT AND APPLY Explain how DNA gyrase works.Ch. 9 - REFLECT AND APPLY Explain, and draw a diagram to...Ch. 9 - REFLECT AND APPLY Would you expect to find...Ch. 9 - REFLECT AND APPLY One of the original structures...Ch. 9 - REFLECT AND APPLY What is the complete base...Ch. 9 - REFLECT AND APPLY Why was it necessary to specify...Ch. 9 - REFLECT AND APPLY What would be the most obvious...Ch. 9 - BIOCHEMICAL CONNECTIONS What is the purpose of the...Ch. 9 - BIOCHEMICAL CONNECTIONS Explain the legal and...Ch. 9 - BIOCHEMICAL CONNECTIONS A recent commercial for a...Ch. 9 - REFLECT AND APPLY A technology called PCR is used...Ch. 9 - REFLECT AND APPLY Why does DNA with a high AT...Ch. 9 - RECALL What are the three primary RNA types?Ch. 9 - RECALL What determines the base sequence of all...Ch. 9 - RECALL What is the name of the process that...Ch. 9 - RECALL What is the basic purpose of tRNA?Ch. 9 - RECALL The base sequence of which type of RNA is...Ch. 9 - RECALL What is the name of the process by which...Ch. 9 - RECALL What are some key differences in how mRNA...Ch. 9 - RECALL What are small nuclear RNAs?Ch. 9 - RECALL What are micro RNAs?Ch. 9 - RECALL Why do we say that micro RNAs are involved...Ch. 9 - RECALL Sketch a typical cloverleaf structure for...Ch. 9 - RECALL What is the purpose of small nuclear RNA?...Ch. 9 - RECALL Which type of RNA is the biggest? Which is...Ch. 9 - RECALL Which type of RNA has the least amount of...Ch. 9 - RECALL What is the role of ATP(CTP): tRNA...Ch. 9 - RECALL What is RNA interference?Ch. 9 - REFLECT AND APPLY Would you expect tRNA or mRNA to...Ch. 9 - REFLECT AND APPLY The structures of tRNAs contain...Ch. 9 - REFLECT AND APPLY Would you expect mRNA or rRNA to...Ch. 9 - REFLECT AND APPLY Which would be more harmful to a...Ch. 9 - REFLECT AND APPLY Explain briefly what happens to...Ch. 9 - REFLECT AND APPLY Explain why a 50S ribosomal...Ch. 9 - RECALL What is long noncoding RNA?Ch. 9 - RECALL How is antisense RNA used to treat...Ch. 9 - RECALL How are miRNA used to treat hepatitis C?Ch. 9 - RECALL How are siRNA used to treat Ebola?Ch. 9 - RECALL What is the difference between miRNA and...Ch. 9 - RECALL Why do researchers believe they can use...Ch. 9 - RECALL Why do researchers believe lncRNA is a...

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