Concept explainers
Interpretation:
The reason behind the belief of researchers that lncRNA is a promising field for developing drug therapies is to be explained.
Concept Introduction:
There are many types of RNAs (ribonucleic acids) that have been discovered in recent years. These include small nuclear RNAs (snRNA) which are found only in the nucleus of a eukaryotic cell and are involved in the processing of initial mRNA (messenger RNA) transcription product to a mature form. Micro RNAs (miRNA) and siRNAs (small interfering RNA) are also discovered recently.
The new RNAs that are discovered block gene expression by various mechanisms. The lncRNA (long non-coding ribonucleic acid) is another type of RNA which is present in thousands and scattered everywhere in the cell. It is defined by transcripts longer than 200
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Biochemistry
- RECALL Are the sequences shown in Question 6 those of RNA or DNA? How can you tell?arrow_forwardREFLECT AND APPLY Why is a trimming process important in converting precursors of tRNA and rRNA to the active forms?arrow_forwardREFLECT AND APPLY Why is it more important for DNA to be replicated accurately than transcribed accurately?arrow_forward
- RECALL What is qPCR?arrow_forwardREFLECT AND APPLY E. coli incorporates deoxyribonucleotides into DNA at a rate of 250 to 1000 bases per second. Using the higher value, translate this into typing speed in words per minute. (Assume five characters per word, using the typing analogy from Question 36.)arrow_forwardRECALL List several ways in which RNA is processed after transcription.arrow_forward
- REFLECT AND APPLY Explain why a 50S ribosomal subunit and a 30S ribosomal subunit combine to form a 70S subunit, instead of an 80S subunit.arrow_forwardREFLECT AND APPLY Is the following statement true or false? Why? The flow of genetic information in the cell is always DNARNAprotein.arrow_forwardREFLECT AND APPLY List three mechanisms that relax the twisting stress in helical DNA molecules.arrow_forward
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning