By Stephanie Dillon with contributions from Sandra Chimon Peszek, DePaul University This laboratory manual contains experiments written specifically to correspond with the Second Edition of General Chemistry: Atoms First by McMurry/Fay. Each experiment covers one or more topics discussed within a chapter of the textbook, with the dual goal of 1) helping students understand the underlying concepts covered in the lecture course, and 2) staying true to an Atoms First Approach. This manual contains thirty-one experiments with a focus on real world applications and a dedication to the Atoms-First Approach. Each experiment contains a set of pre-laboratory questions (also assignable in MasteringChemistry), an introduction, a background section explaining concepts that each student is expected to master for a full understanding of the experimental results, a step-by-step procedure (including safety information), and a report section featuring post-laboratory questions.