Table of Contents Introduction to Pathophysiology PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY Unit 1: The Cell 1. Cellular Biology 2. Genes and Genetic Diseases 3. Altered Cellular and Tissue Biology 4. Fluids and Electrolytes, Acids and Bases Unit 2: Mechanisms of Self-Defense 5. Innate Immunity: Inflammation and Wound Healing 6. Adaptive Immunity 7. Infection and Defects in Mechanisms of Defense 8. Stress and Disease Unit 3: Cellular Proliferation: Cancer 9. Biology, Clinical Manifestations, and Treatment of Cancer 10. Cancer Epidemiology 11. Cancer in Children PART TWO: BODY SYSTEMS AND DISEASES Unit 4: The Neurologic System 12. Structure and Function of the Neurologic System 13. Pain, Temperature, Sleep, and Sensory Function 14. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function 15. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction 16. Alterations of Neurologic Function in Children Unit 5: The Endocrine System 17. Mechanisms of Hormonal Regulation 18. Alterations of Hormonal Regulation Unit 6: The Hematologic System 19. Structure and Function of the Hematologic System 20. Alterations of Hematologic Function 21. Alterations of Hematologic Function in Children Unit 7: The Cardiovascular and Lymphatic Systems 22. Structure and Function of the Cardiovascular and Lymphatic Systems 23. Alterations of Cardiovascular Function 24. Alterations of Cardiovascular Function in Children Unit 8: The Pulmonary System 25. Structure and Function of the Pulmonary System 26. Alterations of Pulmonary 27. Alterations of Pulmonary Function in Children Unit 9: The Renal and Urologic Systems 28. Structure and Function of the Renal and Urologic Systems 29. Alterations of Renal and Urinary Tract Function 30. Alterations of Renal and Urinary Tract Function in Children Unit 10: The Reproductive Systems 31. Structure and Function of the Reproductive Systems 32. Alterations of the Reproductive Systems Including Sexually Transmitted Infections Unit 11: The Digestive System 33. Structure and Function of the Digestive System 34. Alterations of Digestive Function 35. Alterations of Digestive Function in Children Unit 12: The Musculoskeletal and Integumentary Systems 36. Structure and Function of the Musculoskeletal System 37. Alterations of Musculoskeletal Function 38. Alterations of Musculoskeletal Function in Children 39. Structure, Function, and Disorders of the Integument 40. Alterations of the Integument in Children