Hemophilia Essay

explain why I feel this way. Based on the information given, the child's probable diagnosis is Hemophilia. Hemophilia is a genetic disorder that prevents blood from clotting properly. Clotting helps stop bleeding after a cut or injury. Without clotting, a wound can bleed too much either internally or externally. (“Bleeding Disorders in Children,”n.d.) According to Griffin (Griffin, 2015) Hemophilia mostly affects boys (about one in every 5,000-10,000). Girls who inherit the gene rarely get the

probable diagnosis? As the best of my knowledge I believe the two year old child is suffering from an inherited disorder called hemophilia. The Mayo Clinic describes hemophilia as a rare blood disorder that lacks sufficient blood clotting proteins. (Staff, B.M. ((n.d.)). Hemophilia. Retrieved September 27, 2016, from http://www.mayoclinic.org/disease-conditions/hemophilia/basics/treatment/con-20029824 3.

Lastly hemophilia C is the rarest and occurs in 1 in 100,000 of the general population. Most people have the severe type of this disorder. Hemophilia doesn’t occur mainly to a specific race but mainly occurs in men because hemophilia is an X-linked disorder. To make a diagnosis doctors take a blood test to determine if blood is clotting correctly, if not doctors will do clotting factor tests, called factor assays to conclude the type and severity of hemophilia that the patient has.

hemophiliacs have to be cautious of. Hemophilia is a rare blood disease that interferes with the body’s ability to create protein-clotting factors, which is a special protein that is essential

A large number of mutations for Hemophilia A have been detected and identified. The most common mutation found is the intron twenty-two inversion and intron one inversion of the Factor VIII gene. This mutation occurs in 40-50 percent of people with Hemophilia A. It is caused by the homologous recombination between copies of a DNA sequence. One copy is located on the intron 22 region of factor VIII and the other copies are distal to the factor VIII. Intron one of the factor VIII gene occurs when the

getter and transition to get to thesis) Attention Getter: About 400,000 people are living with hemophilia, a rare blood disorder that causes blood to clot abnormally. Many of these people also develop HIV and AIDS, an immune deficiency. Even more shocking is the 78 million people living with HIV. All of these conditions are lifelong and fatal. Over 40 million people each year die of HIV or hemophilia. What 's even more terrifying is the amount of misinformation pertaining to these subjects, such

Blundell, a british obstetrician, successfully performed a transfusion for a patient with postpartum hemorrhage in 1818 and later performed 10 more and half were successful. In 1840, Samuel Armstrong Lane helped with the first transfusion to treat hemophilia and in 1867, and English surgeon named Joseph Lister used antiseptics to reduce the risk of infections during transfusions. In 1900 an Austrian physician discovered the first 3 human blood groups, A, B, and C that was later renamed O. Hepatitis

clinical trial for the treatment of hemophilia with gene transfer showed transient achievement of efficacy in the highest dose cohort tested, but also exposed a previously hidden barrier to the future success of these treatments.” (Gene Therapy for Haemophilia) Recently, the focus of gene therapy strategies is mostly on gene addition rather than gene replacement. The most common approach in gene replacement therapy is through viral vectors. A piece of DNA is

According to the National Hemophilia Foundation (n.d.), von Willebrand disease (VWD) is a genetic disorder caused by missing or defective von Willebrand factor (VWF), a clotting protein. VWF binds factor VIII, a key clotting protein, and platelets in blood vessel walls, which help form a platelet plug during the clotting process. The condition is named after Finnish physician Erik von Willebrand, who first described it in the 1920s (National Hemophilia Foundation, n.d.). The seriousness

There are two types of Hemophilia, type A and type B, Hemophilia A is associated with blood clots after injury or a type of surgery, Hemophilia A is a disease in which a type of protein that is used to stop clotting is changed or mutated. This all starts after the bleeding has begun, little molecules send out a signal for a protein called factor 12 to be activated, then this protein goes on to activate other proteins till the protein Fibrinogen is activated which stops the bleed and forms a stable