Abciximab

This issue could further be addressed by using radial as opposed to femoral access when carrying out pPCI. A trial found that there was a reduced incidence of major bleeding and vascular site complication with a radial approach. Events occurring in 1.4% of those treated with radial approach and 7.2% P<0.0001 of those with femoral access with a reduction in the rate of net adverse clinical events (NACE) defined as “a composite of death, myocardial infarction, stroke, and major bleeding/vascular complications”

Strategies to reduce bleeding have become an integral component of current PCI practice to decrease adverse outcomes 1,2. Bivalirudin, a direct thrombin inhibitor, has been demonstrated in multiple large-scale randomized trials to reduce major bleeding events after PCI among patients presenting with STEMI compared with UFH 3,8. However, bleeding reductions associated with bivalirudin therapy have occurred at the expense of increased rates of acute stent thrombosis 3,4,6,8. These trials have also

Introduction Acute coronary syndrome (ACS) refers to a group of conditions with clinical symptoms similar to acute myocardial ischemia, including pressure-like chest pain associated with nausea and sweating (1). It includes non-ST segment elevation myocardial infarction (NSTEMI), ST-segment elevation myocardial infarction (STEMI), and unstable angina (UA). ACS patients are at increased risk of myocardial infarction and death, therefore, the moderate- to high-risk patients with ACS are treated

Acute coronary syndrome (ACS) refers to a group of conditions with clinical symptoms similar to acute myocardial ischemia, including pressure-like chest pain associated with nausea and sweating (1). It includes non-ST segment elevation myocardial infarction (NSTEMI), ST-segment elevation myocardial infarction (STEMI), and unstable angina (UA). ACS patients are at increased risk of myocardial infarction and death, therefore, the moderate- to high-risk patients with ACS are treated with early cardiac

ST-elevated myocardial infarction (STEMI) is one of the leading causes of death across the world. This has led to researchers attempting to find out what form of treatment is the most effective. This literature review aimed to look at the evidence supporting primary percutaneous coronary intervention (pPCI) as opposed to fibrinolysis for the treatment of STEMI. Primary PCI was found to provide better outcomes of reduced death, re-infarction and intracranial haemorrhage in most patients in a number

CLINICAL CLARIFICATION • Acute coronary syndrome refers to several potentially life-threatening conditions associated with acute myocardial ischemia and/or infarction most commonly resulting from a sudden decrease in coronary blood flow8, 2 • Includes ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina CLASSIFICATION • Based on electrocardiogram (ECG) 8 ○ Acute chest pain and persistent (>20 min) ST-segment elevation – Defined as ST-elevation

Cardiovascular Case Study Mr. Smith is a 56-year-old Caucasian man who is being evaluated in the emergency room with progressively worsening chest pain that began 2 hours ago. The patient describes the pain as pressure in the center of his chest. He rates his pain 7/10. He reports the pain is now radiating down his left arm and through to his back, he is diaphoretic, and complaining of shortness of breath. He denies nausea or vomiting. Mr. Smith reports no previous history of chest pain or pressure