Adenocarcinoma

World Health Organization (WHO) classification6 has defined the non-invasive (adenocarcinoma in situ), minimally invasive adenocarcinoma and invasive lepidic adenocarcinoma ; has replaced the 'mixed subtype category ' in the WHO 2004 classification7 with the predominant subtype ; included the micropapillary subtype8,9 and replaced the term “mucinous bronchioloalveolar carcinoma(BAC)” with invasive mucinous adenocarcinoma. This study aimed to do a comprehensive histological subtyping and detailed

pancreas sits somewhere down in the stomach and is in close vicinity to numerous important structures, for example, the small intestine (the duodenum) and the bile pipes, and in addition critical veins and nerves. The indications of pancreatic adenocarcinoma don't generally show up in the disease's initial stages and are individually not different to the illness. The indications at diagnosis shift as per the area of the tumor in the pancreas, which anatomists divide into the thick head, the neck,

Dyslipidemia is a pathological alteration of lipid and lipoprotein concentrations in the blood. It is one of the main elements of metabolic syndrome. Epidemiological studies have shown that persons with the metabolic syndrome have an increased risk of colorectal cancer (CRC). One of the possible mechanisms is that lipids and lipoproteins have been found to be associated with neoplastic processes as well as inflammation, insulin resistance and oxidative stress. On the other side, some of the factors

TTF-1 ( Nkx2-1), a homeodomain-containing nuclear transcription factor has been a marker in the diagnosis of lung adenocarcinomas and in differentiating them from tumors of other origin.(1) Nkx2-1 is known for its transcriptional activity in the developing lung, thyroid and forebrain. Altered expression of TTF-1 resulting from mutations, polymorphisms and/or epigenetic modifications can predispose an individual to developmental disorders including thyroid dygenesis and thyroid cancer.(2) Mutations

Aetiology and Risk factors There are two main histological variations of gastric adenocarcinoma. The most-common is the “intestinal type,” hence named as of its morphologic similarity to adenocarcinomas ascending in the intestinal tract. The less-common diffuse type stomach cancers are characterized by a lack of intercellular adhesions, which leaves them incapable to procedure glandular structures. PRECURSOR LESIONS FOR INTESTINAL TYPE CANCERS  1. Atrophic gastritis - Is an autoimmune disorder

case of pancreatic adenocarcinoma diagnosed following work up for eosinophilia is reported. A 68 year old female was referred to our Hematology clinic for an absolute eosinophil count of 1869 per microliter. No allergic signs or symptoms were reported. Laboratory studies for parasitic infestations autoimmune disease and collagen vascular disease were negative. Computed Tomography of the abdomen revealed a mass in the neck of the pancreas with biopsy consistent with adenocarcinoma. The patient received

In this study resected samples of primary gastric adenocarcinoma who received curative surgery without any preoperative treatment were randomly selected and enrolled into a dual-block group cohort with the aim of testing two primary tumour blocks.A total of 274 cases were prospectively assigned after obtaining consent for the study.Patients details ,including age,sex,and tumour location,differentiation and Lauren classification were recorded. The excised specimen were fixed immediately in 10%

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal and the most common type of pancreas cancer as it accounts more than 85% of all neoplasms. (1,2) It has high incidence rate worldwide with around 300,000 new cases projected to be diagnosed every year. (3) In men, it is the fourth cause of death related to cancer whereas in women it is the fifth cause. (4) 1.1 Risk factors The real causes of PDAC are not well known. (5) However, many risk factors are associated such as smoking which increases

REASON CHIEF COMPLAINT: Stage IV adenocarcinoma of unknown primary favoring a pancreatobiliary origin. HISTORY OF PRESENT ILLNESS Mr. Sullivan is a very pleasant 31-year-old gentleman who presents with a stage IV adenocarcinoma of unknown primary favoring a pancreatobiliary origin. In 10/2017, he presented to outside hospital with constant abdominal and back pain for 2-3 months. A CT scan was done which showed a multifocal hypodense lesions throughout the liver with retroperitoneal adenopathy

1 Abstract Despite decades of research, pancreatic ductal adenocarcinoma (PDA) has become the third leading cause of cancer-related deaths in the United States. In fact, by 2020, it is projected to become the second leading cause of cancer-related deaths in the United States. Personalized, or precision medicine, has resulted in improving patient outcomes in other tumor systems. However, for pancreatic cancer patients, there are a limited number of evidence-based targeted therapeutic options that