Anaemia

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  • Sickle Cell Anaemia

    391 Words  | 2 Pages

    Sickle cell anaemia describes a hereditary autosomal recessive disorder that affects a protein found in red blood cells (erythrocytes) called haemoglobin. This disease results in 100% of blood cells becoming sickle shaped. The co-dominant sickle cell disease entails half of the erythrocytes becoming sickle shaped and the remaining half as normal biconvex structures, however, these people are carriers and can pass the disease or anaemia onto their offspring. Prevalence of significant morbidity and

  • Sickle Cell Anaemia Essay

    584 Words  | 3 Pages

    chains3. In addition, these disorders can be of various conditions, however, we will mostly on the two most known conditions which are sickle cell anaemia (HbSS) and sickle cell trait (HbAS). The other conditions are those where sickle cell disorders is associated with other disorders such as beta thalassaemia or haemoglobin C (HbSC). Sickle cell anaemia refers to the form of sickle cell disorders where the patient receives a copy of the mutated gene from each of his parents (homozygosity) whereas

  • Sickle Cell Anaemia Research Paper

    491 Words  | 2 Pages

    SICKLE CELL ANAEMIA • ABOUT SICKLE CELL ANAEMIA: Sickle cell anaemia is due to inherited red blood cell disorder. People with this disorder have sickle haemoglobin or haemoglobin S which is abnormal haemoglobin in their red blood cell. Sickle cell anaemia occur when the people have haemoglobin SS which is derived from two haemoglobin S genes, one from each parents • CAUSE OF SICKLE CELL ANAEMIA: This disorder is caused by mutation at sequence of three nucleotides in DNA that specifies a particular

  • Can Sickle Cell Anaemia Be Cured?

    3101 Words  | 13 Pages

    Can Sickle Cell Anaemia be Cured Effectively in Adults? 1.1 Identification of a Biological Issue Sickle cell anaemia is a disorder affecting the red blood cells and up to 100,000 people are estimated to have the disease in the USA (Centre for Disease Control). Due to a genetic mutation in the gene responsible for the production of haemoglobin (MayoClinic, 2014) the red blood cells, which are usually a biconcave disk in shape, become sickle (bent) shaped (Figure 1) and the haemoglobin that the red

  • Effects Of Hydroxyurea On People With Sickle Cell Anaemia

    1415 Words  | 6 Pages

    associated with hydroxyurea can affect many sufferers in a negative way and lead to a poorer quality of life. The symptoms can lead to depression and emotional distress. In some cases, the symptoms may require hospitalization. As people with sickle cell anaemia are more susceptible to infections, for this reason they may be required to avoid crowded places and some social situations. Anxiety and depression can lead to feelings of helplessness, sadness and loneliness, which can keep patients isolated. Sufferers

  • Sickle Cells Anaemia And The Sickle Cell Trait

    910 Words  | 4 Pages

    UNDERSTANDING SICKLE CELL ANAEMIA AND THE SICKLE CELL TRAIT Introduction Sickle Cell Anaemia is the commonest of most severe form of Sickle Cell Disease. SCD is a collective term for hereditary haemoglobinopathies caused by the inheritance of a mutated haemoglobin allele (sickle haemoglobin-HbS) in the erythrocytes. The HbS mutation is caused by a Valine to Glutamic acid substitution at the 6th amino acid of the β-globin chain. (Harmon et al., 2012)The first known case of SCD in the western world

  • PCR Gel Electrophoresis Introduction Sickle cell anaemia is caused by a Single Nucleotide

    1200 Words  | 5 Pages

    Electrophoresis Introduction Sickle cell anaemia is caused by a Single Nucleotide Polymorphism (SNP). SNPs are the most common type of genetic variation, with each SNP representing a difference in a nucleotide. SNPs occur normally throughout a person’s DNA. Most commonly, they are usually found in non-coding regions and have no effect on health. When a SNP occurs in a coding region, it may play a direct role in disease by affecting the gene’s function. This SNP for sickle cell anaemia produces the recognition sequence

  • Diagnosis Of The Patients With Chronic Kidney Disease

    1850 Words  | 8 Pages

    chronic kidney disease (CKD) increasing worldwide and its economic repercussions, a detailed haematological workup of such patients is necessary to detect the type of anaemia, as there is a general tendency to consider anaemia to be of the normocytic normochromic type. However in India, a co-existing iron deficiency is also common. Anaemia is an independent risk

  • A Short Note On Beta Thalassemia And Its Effects On African Descent

    1337 Words  | 6 Pages

    BETA THALASSAEAMIA Beta-thalassemia is known as one of the most common autosomal recessive disorders around the world (Coa et al, 2010). This condition is seen the most in populations of Central Asia, Mediterranean, Far East Indian subcontinent and populations of African descent. When it comes to the highest incidence, the island of Sardinia in Italy (12%), Cyprus (14%) and South East Asia are amongst the highest (Coa et al, 2010). Population, which have high gene frequency of beta- thalassemia

  • Environmental Factors Affecting The Disease Essay

    1454 Words  | 6 Pages

    have the second and consequent attacks after exposure to infection. Environmental factor-The disease is seen throughout the year, but higher incidence is reported during rainy season and increased fly breeding in June-September, because the disease is spread mainly due to flies. Social factor-Drinking water or milk and food contaminated by intestinal contents of the patients or carriers or by flies which often transmit the disease. Eating unwashed and uncooked vegetables are good source of infection

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