Antibiotic resistance

2015 Title Introduction When an individual gets sick from a bacterial infection, antibiotics have undoubtedly changed the lives of many people by saving them from death (Davies, 2010). Since the discovery of antibiotics, scientists have been finding ways to improve the effectiveness of antibiotics. For the past decades, there’s been an alarming increase of antibiotic resistance globally (Witte, 2006). Antibiotics should ideally get rid of infectious diseases but instead the bacteria are finding

Antibiotic Resistance The increasing resistance of bacteria to antibiotics is a growing problem that affects individuals on a global status. Antibiotic resistance refers to the ability of bacteria to alter their genetic material and mutate to avoid destruction by antibiotic medications rendering the drugs ineffective in fighting infection and disease. This resistance has had tragic effects as numerous of the resistant infections have resulted in death of the host. Because of the severity of this

Phosphoethanolamine Transferase EptA Contribution to Antibiotic Resistance The Centers for Disease Control and Prevention (CDC) estimated the number of mortality caused by Multi-Drug Resistant Bacteria (MDRB) in the United States alone to be at 23,000 annually (CDC, 2017). As the number of cases increases, scientists are urged to reform a new tactic to tackle this challenge. A BBC article reports that scientists in the University of Western Australia were able to model a three-dimensional shape

about the determination of Antibiotic resistance that relies on the fitness effects of resistance elements in the absence of antibiotics. Angst and Hall tentatively developed rifampicin-resistant and delicate Escherichia coli in drug-free environment, before measuring the impacts of new resistance components on fitness in antibiotic free conditions. Streptomycin resistance changes had little fitness impacts in rifampicin-resistant genotypes that had adjusts to antibiotic free environment , contrasted

are resistant to antibiotics, it will be more difficult and more expensive to treat human bacterial infections. When antibiotics fail to work, consequences include extra visits to the doctor, hospitalization or extended hospital stays, a need for more expensive antibiotics to replace the older ineffective ones, lost workdays and, sometimes, death. Antibiotics are called "societal drugs," since antibiotic resistance can pass from bacterium to bacterium (see About antibiotic resistance), and resistant

Introduction Antibiotics are amongst the most important medical discoveries and their introduction represents a remarkable success story (Hedin, 2011). The term antibiotics literally means against life (Walsh, 2000). Thus antibiotics can be used against any microbe such as bacteria, viruses, fungi, and protozoa. However, some people use the term to only apply to bacteria, but in this paper, the more appropriate term will be used. Widespread use of antibiotics has been very controversial in the

rise in antibiotic resistance. Some bacteria that can cause serious disease are becoming resistant to most commonly available antibiotics. Antibiotic medications are used to kill bacteria, which can cause disease and illness. A major contribution to human health is antibiotic medication. Many diseases that once killed people in the past can now be treated effectively with antibiotics. However, it has come to the surface that some bacteria have become resistant to commonly used antibiotics. Antibiotic

exposed to antibiotics, they are not always guaranteed to die. This is called antibiotic resistance. Sometimes antibiotics can only stop the bacteria from multiplying (make it stagnate), and other times it causes the bacteria to multiply even more. These three results depend on antibiotic concentration, bacterial mutation, and bacterial genetic exchange. One big factor in the resistance bacteria show towards antibiotics is antibiotic concentration. Usually, if large amounts of an antibiotic are attacking

previously discussed, antibiotics often work by targeting critical functions of the bacterial cell. This means that antibiotics have specific targets, which is a boon because it means non-microbial life will not be affected by the antibiotics. However, because of this specificity, bacteria can develop ways of protecting themselves from antibiotics, leading to the rise of antibiotic resistance Like any other organism, bacterium are subject to evolutionary pressure. Antibiotic resistance in bacteria is rarely

Antibiotic resistance Key facts • Antibiotic resistance is one of the greatest threats to global health, Food security and development. • Antibiotic resistance can affect anyone of any race, size and gender. • Antibiotic resistance takes place naturally, however misusing antibiotics can increase the process in animals and humans. • Infections can become harder to treat due to antibiotics used to treat the infection or diseases have become less effective. Antibiotics are used to treat and prevent

Antibiotic Resistance: The Setting Antibiotic resistance can develop wherever antibiotics are: medical facilities, animal products and communities. Breaks in infection control, inadequate water sanitation and poor hygiene all contribute to the spread of resistant bacteria from person to person (Collignon, et al., 2015). The majority of antibiotic usage worldwide is in animals raised as a food source (Collignon, et al., 2015). 80% of antibiotic use in the United States is for growth promotion and

Antibiotics are powerful very frequently used potential drugs in fighting bacterial infections worldwide, [1]. These agents saved millions of lives in the past fifty years in both hospital-based and outpatient settings. Inadequate measures to control the spreading of infections, overprescribing as well as inappropriate selection and dosing of antibiotics by healthcare providers, unfettered access to antimicrobials by public, failure to adhere to clinically desired treatment regimens are some of the

ANTIBIOTIC Antibiotics are a term refers to substances produced by microorganisms that can harm and inhibit or destroy other microorganisms, specifically bacteria (15). Antibiotics can be produced naturally or unnaturally via pharmaceutical industries using large-scale processes of fermentation. The antibiotics discovery has been of great significance due to in many clinical settings the antibiotics generally are the best way to destroy bacteria which cause infections in humans and animals. In 1910

For many years people have wondered why the antibiotics that are used so commonly nowadays are not as effective as they once were. Just like organisms evolve throughout time, resistance to certain things can also evolve. This resistance however is not something that happens naturally but rather is a man-made process which was caused via the misuse, overuse, and/or underuse of antibiotics (Davies 2010). The author Davies explains that there is no better example of the Darwinian notions of selection

Antibiotic Resistance Nicholas J. Ciotti Nova Southeastern University Biology 1510 Professor A. Hirons March 28, 2011 Abstract Antibiotic resistance is when microorganisms, such as bacteria, are able to survive an exposure to antibiotics and these bacteria are now resistant to the effects of these antibiotics. Antibiotic resistance in bacteria has been an issue since antibiotics were discovered. The fact that bacteria can become resistant to our medical treatments such as antibiotics

Introduction Antibiotic resistance is one of the greatest threats to global health, food security and development today, it occurs naturally, but the pace of its process speeds up its abuse when given to humans and animals and it can harm anyone regardless of age and country of residence (Laxminarayan, et al.2013). According to World Health Organization (WHO), there are 700,000 people death every year because of antibiotic resistance (WHO,2016). A study by the Public Health Foundation in England

“superbug” that was resistant to every antibiotic available in the U.S., a sobering incident to the medical community. The patient was infected with Klebsiella pneumoniae bacteria that had become resistant to cabapenems (a class of antibiotics that are typically used as a last resort when other antibiotics have failed), therefore becoming a “Carbapenem-Resistant Enterobacteriaceae” (CRE). The bacteria was discovered to be resistant to no less than 26 different antibiotics. Such a story could potentially

"Antibiotic Resistance" I. Abstract When penicillin was first administered in 1943, it proved to be extraordinary at wiping out nasty cases of syphilis, tuberculosis, gonorrhea, and meningitis infection. With the threat of these deadly infections in ‘check,’ pharmaceutical industries then cut back on their research to discover even more effective antibiotics. This new-found medical confidence inspired patients to merrily run to the clinic to get penicillin prescriptions for everything from

Introduction The question of antibiotic resistance is a growing phenomenon in contemporary society and modern medicine; it pertains to pathogenic organisms and is one of the most eminent issues of public health in the twenty-first century. Though resistant genes are ancient, its increasing prevalence poses a threat. It demands a greater need for antibiotic therapies. New resistance mechanisms may spread globally and limit our ability to treat disease and lead to a giant hole in the pillars of modern

Antibiotics are an integral part of life today, without them the quality of life on Earth would be much different. Antibiotics are any substance that inhibits microbes, such as bacteria, by slowing down its growth or killing it. This is accomplished by targeting specific cellular processes or mechanisms of the microbe and altering or inhibiting them. Antibiotics occur naturally and are abundantly present in the environment. A large variety of microorganisms produce antibiotics, for example fungi