harmful effects of this food additive on astrocytes and neurons. When ingested, aspartame is metabolized into phenylalanine (50%), aspartic acid (40%), and methanol (10%), which each affect neuronal cells differently (Ashok, Sheeladevi, and Wankhar, 2014). According to Rycerz and Elżbieta Jaworska-Adamu (2013), the excess phenylalanine blocks the transport of amino acids, glutamine, histidine, methionine, serine, threonine, tyrosine and tryptophan,
The article Leading Scientists Around the World Confirm Safety of Aspartame has several problems with their reasons that aspartame is safe. The expert team concluded through controlled scientific studies that aspartame is safe. The study also states, “Aspartame is a well-characterized, thoroughly studied, high intensity sweetener that has a long history of safe use in the food supply and can help reduce the caloric content of a wide variety of foods” (Leading Scientists). If aspartame is safe than
to aspartame in diet soda contributing to cancer, it also causes memory loss. Carbonated beverages began containing aspartame in 1983, after the US Food and Drug Administration (FDA) approved it (Gold, 1995). Aspartame contains 40% aspartic acid, which is an amino acid that increases the level of aspartate and glutamate in blood plasma, according to Gold (1995). This increase of aspartate, as explained by Gold (1995), causes over stimulation of the nerves by acting within the brain as neurotransmitters
over the world. Aspartame is one of the most common artifical sugar subsitute used, which is sold under the brand names NutraSweet and Equal. It is a non sachharide sweetner, made by coupling of two amino acids (Phenylalanine and Aspartic Acid) together. It is a methly ester of the aspartic acid and phenylalanine dipeptide. Aspartame is used as it is 200 times more sweeter than sugar, so a very less amount is used in replacement of sugars giving lowest calories. History M. Schlatter, a chemist working
building blocks)? Amino acids are the smaller building blocks which protein is made of. There are 20 different amino acids. Depending on length, sequence of amino acids and function; each protein has unique different from each other. These amino acids have unique 3D shapes by fold up in complex ways. 2. List the amino acids and diagram their organic structure (C-N bonds). The 20 different amino acids are alanine, arginine, asparagines, aspartic acid, cysteine, glutamic acid, glutamine, glycine,
In essence, toxicology is the science of poison, toxicants, or toxins. A poison toxicant, or toxic is a substance capable of causing harm when administered to an organism. Harm is defined as seriously injuring or causing the death of an organism. The term toxicant can be a synonym for poison, or the term poison might be appropriate for the most potent substances. The term toxin usually refers to a poison derived from a protein or conjugated protein produced by some higher plant, animal, or pathogenic
Hypothesis: If a polar amino acid is adsorbed by a polar matrix, then the polar matrix will not move as far along the matrix as a hydrophobic amino acid. If this is so, the Rf value of a polar amino acid will be relatively small to that of a non-polar amino acid. Introduction: In order to identify whether an amino acid is polar (hydrophilic) or non-polar (hydrophobic), the process of chromatography is used, which separates the amino acids and identifies them based on specific chemical traits given
mixture of amino acids based on their produced charge. Isoelectric point is a pH where the given amino acid has a no charge thus; produces a neutral structure. With a pH above the isoelectric point will cause the amino acid to be deprotonated and thus; produce a negative charge where as a pH lower than the isoelectric point will cause the amino acid to be protonated and thus; hold a positive charge. 2. In the experiment a cation exchange column was used to separate the mixture of amino acid. Cation exchange
dipeptide of the two naturally occurring amino acids L-aspartic acid and L-phenylalanine. The term methyl ester refers to an ester that produces methanol when hydrolyzed; hydrolysis being the breakdown of a large molecule into smaller ones with the addition of water. Aspartic acid or aspartate has the chemical formula C4H7NO4, and contains an amino-group, a carboxylic acid group, and a side chain CH2COOH. It is categorized as an essential amino acid found in all proteins, which the body can naturally
ionization of amino acids, through examining the titration curve thus determine pKa values to recognize the unknown amino acid Proteins are formed by polymerizing monomers that are known as amino acids and can fulfill various functions in an in the body. The body is made from 20 different amino acids differ in characteristics and functions that depend on the order of amino acids that make up the protein. Amino acids are compounds containing an amine group, -NH2, and a carboxylic acid group, -COOH. In