Chagas disease

CHLP 4623 Disease Report: Chagas Disease Hannah M. Lahodny || Dr. Jones || December 16th 2014 Introduction Discovered in 1909 by Carlos Chagas, Chagas disease, or American trypanosomiasis, affects an estimated 8 million individuals annually according to the Centers for Disease Control and Prevention. The number of individuals affected by this disease annually makes it a significant, yet preventable, problem. As a chronic parasitic infection, the disease is transmitted by insects and

Chagas disease occurs in two stages. The severity and course of infection might be different in people infected at different times in life and in different ways. The first stage is the acute stage, which is characterized by the presence of chagomas. This stage lasts for the first few weeks or months of infection. It usually goes unnoticed because it is either asymptomatic, or the infected only exhibit signs/symptoms that are not entirely unique to the disease. This includes headaches, rash (chagomas)

Disease will always be prevalent across the world, there is no place where disease is non-existent and every single region across the world has its own varieties of diseases. Most of them are different, but they all have one thing in common, they destroy the life of a human by either bringing birth to acute symptoms or chronic ones and sometimes even death. Our focus though, will not be on every single region, but particularly in the tropics, home to malaria, hookworm, yellow fever, and most important

Nature & History of the disease Chagas disease, also known as American Trypanosomiasis, is a tropical disease caused by the parasite Trypanosoma cruzi, transmitted to humans through contact with the feces of an infected triatomine bug. The triatomine bug known as the kissing bug is a subspecies of the Reduviidae family. The bug itself does not cause the disease. Through contact with the fecal matter from the kissing bug, which is excreted near the bite wound, the parasite enters the bloodstream

America, American Trypanosomiasis, or better known as Chagas Disease, is a “systematic chronic parasitic infection by Trypanosoma cruzi” (Ramos, et al. 919). It was discovered in 1909 by a Brazilian researcher named Carlos Ribeiro Justiniano Chagas, which was where the disease obtained its name from. Chagas Disease has expanded from Latin America to other countries, including Mexico. Rural areas are at great risk of this of developing this disease, but migration has been a key factor for the expansion

known as Chagas disease, where outbreaks are most common in underdeveloped countries. Shikanai-Yasuda and Carvalho (2012) concluded the etiologic agent of the disease forms in the blood and fluid of infected animals and humans and is transmitted at the bite sites of the triatomine bugs feces. The Amazon Basin in Brazil has experienced another form of transmission, orally, which is now considered the principal form of Chagas disease in the country. The outbreaks of orally transmitted Chagas in Brazil

causes African sleeping sickness in humans and nagana in livestock, and to Trypanosoma cruzi (Tc), that causes Chagas ' Disease. Hexokinase (HK), the first enzyme in the glycolytic cycle, is a potential and valid target for antitrypanosomal chemotherapy. The three dimensional (3D) structure of a drug target is vital to obtain a comprehensive understanding of the molecular basis of a disease, to gain insights on the impact of genetic variations on the protein structure and function, and to investigate

Full Blood Count is a test used to evaluate the composition and concentration of the cellular components of blood such as red blood cells, white blood cells, platelets, etc. The abnormality it could identify are anaemia which means that there are less red blood cells or less haemoglobin in red blood cells than normal; polycythaemia which means there are too many red blood cells due to various causes; leucopoenia which means there are too few white cells due to various causes; leucocytosis which

Chagas Disease Chagas disease is an illness caused by the parasite Trypanosoma cruzi. This parasite infects triatomine bugs, which are common in Mexico, Central America, and South America. These bugs spread the disease to humans through contact with their feces. This may be through bites from the bugs, or the parasite can enter the body through mucous membranes or small cuts in the skin. Chagas disease has two phases. In the initial (acute) phase of infection, Chagas disease may or may not cause

A man named Carlos Chagas found the Chagas Disease. He was born in Oliveria, Brazil on 1879. Their family owned a coffee plantation. Carlos’s father passed away when he was around 4 years old. His mother wanted him to study engineering, however, his uncle, who was a physician, sparked his interest in medicine. He told Carlos that Brazil was not industrializing due to endemic disease that was in the country. In 1896, Carlos Chagas studied at Rio de Janeiro. He chose “Hematological Aspects of Malaria”