Chromosomes

Schizophrenia: Research progress of chromosomes 22 and 8 Present to: Geraldine Boyden By: Quiana Jones Core Articles: Gill M, Vallada H, Collier D et al: A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Am J Med Genet Neuropsychiatr Genet 1996; 67: 40–45. Polymeropoulos MH, Coon H, Byerley W, et al: Search for schizophrenia susceptibility locus on human chromosome 22. Am J Med Genet 54:93-99, 1994

Genetic testing is a class of medical testing that recognize changes in chromosomes, gene or proteins. This type of test look for abnormalities in DNA or RNA that is collected from a person’s blood, body fluids or tissues. Genetic testing scans the genes looking for large or small change that occur to gene. These changes to the genes could have missing or addition parts that could change the chemical base within the DNA strand. Abnormal genes could be the result of other mistakes like the genes

INTRODUCTION: The Sex chromosome(X and Y) originates from a pair of autosomes (H.J. Muller, 1914) about 350million years ago in reptile-like ancestors (Charlesworth, 1991; Graves, 1995). Environmental factor like temperature determines sex in some species e.g. crocodiles and turtles (Bull et al, 1975). In humans, there are 22 pairs of chromosomes called the Autosomes and one pair of sex chromosome (X-Y) which makes a total of 23pairs of chromosomes. These 23pairs (46) chromosomes are contributed by

Using P-element Induced Male Recombination to Generate a Deletion in the DMAP1 Gene on Chromosome Two in Drosophila melanogaster Abstract: The goal of this study was to induce a deletion in the DMAP1 gene on chromosome two in Drosophila melanogaster through P-element mobilization. The DMAP1 gene may be an essential gene, however not much is known about it. We attempted to uncover the function of DMAP1 by creating a series of genetic crosses and selecting for brown-eyed non-stubble male flies

and mammoth nucleus. Then again let us assume that we find an intact nucleus having a proper DNA inside it, there are still many obstacles to overcome. One being lack of enough knowledge and information about the number of chromosomes that mammoths possessed. Moreover, Y chromosome in a mammal is typically very small and repetitive, therefore, making it hard to sort it out. But, the solution can be sequencing only the female species. Also, determining the exact sequence of other regions including centromere

The book The Philadelphia Chromosome by Jessica Wapner follows the story of how a fatal disease called Chronic Myeloid Leukemia became one of the first targets of kinase inhibitors for targeted cancer therapies. Chronic Myeloid Leukemia (CML) affects only a small number of people (an estimated 8,500 diagnoses this year), but was until recently considered a fatal disease. Gleevec, a drug created by Novartis (mostly) that targeted the BCR/ABL protein in CML patients. This protein causes a tyrosine

Have you ever thought about having a clone of yourself? What it would be like to have second chances with every organ and tissue in your body? Well in Chromosome 6, written by Robin Cook, that is exactly how their lives worked. The clones were grown to benefit the individuals who worked around the idea, envisioning a new technique to help all individuals in the world.Yet with new testing and ideas cause different opinions and ethical views on the topic. While reading the book, it becomes clear that

Introduction Human chromosomes are incredibly complex, containing a variety of different structures necessary to maintain its function; one of these is called a Telomere and is found at the ends of the chromosomes. Telomeres contain thousands of repeats of the repetitive TTAGGG DNA sequence; this is combined with a complex enzyme known as telomerase. Furthermore, the function of this ribonucleoprotein enzyme complex is to maintain telomere length in cancer cells by adding TTAGGG repeats onto the

Clearly the choo-choo was chugging faster now — so I scrolled down for backup. My mom? God, no…this would just be confirmation that the Y chromosome should be erased from humanity. My sister? Not much better. Still, it was someone. Mercifully, Hester answered, even though I knew she was at work. "Hester? Got a minute?" "Hey, birthday girl! What's up?" My sister's voice, always on the loud side, boomed out of my phone, and I held it away from my ear. "Hester," I bleated

put towards examining chromosomes 5 and 10 and their association with the disease. “Chromosome 5 is estimated to contain 900 genes making up nearly 6% of all the DNA in the human body.” Several different variations of genes on chromosome 5 have been linked back to other inflammatory bowel diseases (Genetics Home Reference). “Chromosome 10 contains roughly 700-800 genes and makes up about 4.5% of every DNA in the human body.” Researchers don’t have much information on chromosome 10, more specifically