Clostridium difficile

Prevention of Relapse Following Clostridium difficile Infection Using Probiotic Lactobacillus casei Shirota This article, which was submitted for review in 2013, was written by Lennard YW Lee, Ramez Golmohamad, and George MacFaul of the Department of Gastroenterology, Milton Keynes NHS Foundation Trust, Standing Way, Milton Keynes MK65LD, United Kingdom. The paper was accepted for publication August 25, 2013. Clostridium difficile (C. difficile) is an anaerobic, Gram-positive, bacillus-shaped

A Review of Clostridium Difficile Multiple Recurrence Introduction Clostridium difficile is a gram-positive, spore-forming, anaerobic bacillus. Since the turn of the 21st century, there has been a dramatic increase in the number of nosocomial infections associated with antibiotic exposure and an increase in the severity of the disease. Challenges of disease containment include emerging risk factors and recurrence. In 2008 the acute care costs, not including the economic burden placed outside of the

| | | | | Clostridium Difficile | Clostridium Difficile The healthcare professional can expect to encounter various conditions within their scope of experience. Clostridium difficile represents one of the most common and challenging nosocomial infections that can cause life-threatening complications such as hypervolemia, sepsis, pain, and peritonitis (Grossman and Mager 155). The recognition, diagnosis, treatment and inhibition of transmission of this bacterium are

facility along with the administration of an antibiotic may result in a Clostridium difficile infection (CDI). The purpose of this paper is to provide an overview of a CDI, including an overview of the microbiology of Clostridium Difficile (C- diff), as well as the epidemiology, pathophysiology, signs, symptoms, treatment and prevention of the infection. In 2011, there was an estimated 450,000 cases of Clostridium difficile infections in the United States. Of these cases, 83,000 were first occurrence

Clostridium difficile is a bacterium that is found in the human colonic flora that can cause diarrhea and more serious conditions, such as colitis. This occurs if the physiological bacterial flora is changed or damaged due to prolonged antibiotic use and if the concentration of C. difficile increases significantly. The prolonged antibiotic use enables C. difficile to multiply and produce large amounts of dangerous toxins. Therapy for those who suffer from this includes rehydration, immediate stop

Running head: CLOSTRIDIUM DIFFICILE Clostridium difficile Jane Doe A University   Clostridium difficile Pathophysiology Clostridium difficile is a gram positive, spore forming anaerobic bacillus, which may or may not carry the genes for toxin A-B production (Nipa, 2010). These two types of protein exotoxins produced by the Clostridium difficile bacillus, toxin A and toxin B, can have an infectious form and a non-active, non-infectious form (Grossman, 2010). The infectious form can survive

Clostridium difficile and its Effects on the Body Dylan Decluze April 20, 2017 Class Period Dr. Morris Clostridium difficile and its Effects on the Body Clostridium difficile, also known as C. diff, is a bacterium that causes severe symptoms, including inflammation of the colon, which can be life threatening (Centers for Disease Control and Prevention, 2015). It is a very common infection that affects hundreds of thousands in the United States alone. If not caught and treated early, it

Introduction Clostridium difficile was initially thought to be part of the normal flora and C. difficile infections were miss identified as Staphylococcus aureus or Candida albicans. The C. difficile toxin was later identified in 1977 after a clinical trial using clindamycin caused patients to have diarrhea. The next year, in 1978, antibiotic use was quickly discovered as the major risk factor (Brymer, 2007). Clostridia belong to the phylum Firmicutes and comprise a heterogeneous group consisting

Clostridium difficile (C-diff) Symptoms and causes Clostridium difficile (C-diff) is a bacterium of the intestine that usually develops after the start of antibiotics in at risk patients. C-diff causes inflammation of the intestine by irritating the lining of the intestinal wall. C-diff can cause many symptoms with lose stool multiple times throughout the day for more than two days being the most common. Severe infections can lead to hemodynamic changes in the body that could lead to hospitalization

History Clostridium difficile was discovered and isolated from neonates in 1935. It was initially considered a component of the fecal flora of newborns and not thought to be pathogenic (Keessen, Gaastra, & Lipman, 2010). The history of C. diff and other antibiotic resistant pathogens are closely related with the history of antibiotics. The first antibiotic discovered was penicillin by Alexander Fleming while working with Staphylococcus. With this discovery, a surge of natural and synthetic drugs